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Acceptability of antipsychotic transdermal patch for acute schizophrenia: a systematic review and meta‐analysis.

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Title: Acceptability of antipsychotic transdermal patch for acute schizophrenia: a systematic review and meta‐analysis.
Authors: Kishi, Taro (AUTHOR), Citrome, Leslie (AUTHOR), Sakuma, Kenji (AUTHOR), Hamanaka, Shun (AUTHOR), Nishii, Yasufumi (AUTHOR), Iwata, Nakao (AUTHOR)
Source: Psychiatry & Clinical Neurosciences. Apr2024, Vol. 78 Issue 4, p260-262. 3p.
Subjects: Transdermal medication, Drug formularies, Schizophrenia, Publication bias, Medical education, Grants in aid (Public finance), Medical research
Abstract: This article discusses the acceptability of antipsychotic transdermal patches as a treatment option for acute schizophrenia. Antipsychotic medications are commonly used for managing psychosis and preventing relapse in individuals with schizophrenia. While previous studies have shown that long-acting injectable antipsychotics are more effective in preventing relapse compared to oral antipsychotics, the role of transdermal delivery systems remains unclear. The authors conducted a systematic review and meta-analysis comparing the acceptability of transdermal patches versus oral antipsychotics in people with acute schizophrenia. The results suggest that transdermal patches may be more acceptable in terms of all-cause discontinuation rates, potentially due to their favorable tolerability profile and visible proof of adherence. However, further research is needed to fully understand the acceptability and treatment outcomes of different formulations. [Extracted from the article]
Copyright of Psychiatry & Clinical Neurosciences is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: Acceptability of antipsychotic transdermal patch for acute schizophrenia: a systematic review and meta‐analysis.
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  Data: <searchLink fieldCode="AR" term="%22Kishi%2C+Taro%22">Kishi, Taro</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Citrome%2C+Leslie%22">Citrome, Leslie</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Sakuma%2C+Kenji%22">Sakuma, Kenji</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Hamanaka%2C+Shun%22">Hamanaka, Shun</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Nishii%2C+Yasufumi%22">Nishii, Yasufumi</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Iwata%2C+Nakao%22">Iwata, Nakao</searchLink> (AUTHOR)
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  Data: <searchLink fieldCode="JN" term="%22Psychiatry+%26+Clinical+Neurosciences%22">Psychiatry & Clinical Neurosciences</searchLink>. Apr2024, Vol. 78 Issue 4, p260-262. 3p.
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  Data: <searchLink fieldCode="DE" term="%22Transdermal+medication%22">Transdermal medication</searchLink><br /><searchLink fieldCode="DE" term="%22Drug+formularies%22">Drug formularies</searchLink><br /><searchLink fieldCode="DE" term="%22Schizophrenia%22">Schizophrenia</searchLink><br /><searchLink fieldCode="DE" term="%22Publication+bias%22">Publication bias</searchLink><br /><searchLink fieldCode="DE" term="%22Medical+education%22">Medical education</searchLink><br /><searchLink fieldCode="DE" term="%22Grants+in+aid+%28Public+finance%29%22">Grants in aid (Public finance)</searchLink><br /><searchLink fieldCode="DE" term="%22Medical+research%22">Medical research</searchLink>
– Name: Abstract
  Label: Abstract
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  Data: This article discusses the acceptability of antipsychotic transdermal patches as a treatment option for acute schizophrenia. Antipsychotic medications are commonly used for managing psychosis and preventing relapse in individuals with schizophrenia. While previous studies have shown that long-acting injectable antipsychotics are more effective in preventing relapse compared to oral antipsychotics, the role of transdermal delivery systems remains unclear. The authors conducted a systematic review and meta-analysis comparing the acceptability of transdermal patches versus oral antipsychotics in people with acute schizophrenia. The results suggest that transdermal patches may be more acceptable in terms of all-cause discontinuation rates, potentially due to their favorable tolerability profile and visible proof of adherence. However, further research is needed to fully understand the acceptability and treatment outcomes of different formulations. [Extracted from the article]
– Name: AbstractSuppliedCopyright
  Label:
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  Data: <i>Copyright of Psychiatry & Clinical Neurosciences is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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      – Type: doi
        Value: 10.1111/pcn.13635
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      – Code: eng
        Text: English
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        StartPage: 260
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      – SubjectFull: Transdermal medication
        Type: general
      – SubjectFull: Drug formularies
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      – SubjectFull: Schizophrenia
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      – SubjectFull: Publication bias
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      – SubjectFull: Medical education
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      – SubjectFull: Medical research
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            NameFull: Sakuma, Kenji
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              M: 04
              Text: Apr2024
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              Y: 2024
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