Efficacy of lamotrigine in migralepsy: a case report.
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| Title: | Efficacy of lamotrigine in migralepsy: a case report. |
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| Authors: | Iabichella, Giacomo (AUTHOR), Autunno, Massimo (AUTHOR), Bertino, Salvatore (AUTHOR), Laganà, Angelina (AUTHOR), Labate, Angelo (AUTHOR) |
| Source: | Neurological Sciences. May2024, Vol. 45 Issue 5, p2383-2386. 4p. |
| Subjects: | Epilepsy, Migraine aura, Lamotrigine, Seizures (Medicine), Neurological disorders, People with epilepsy, Spreading cortical depression |
| Abstract: | This letter discusses the relationship between migraine and epilepsy, specifically a condition called migralepsy. Migralepsy is characterized by a seizure that occurs during or within one hour after a migraine with aura. The letter describes a case of a 22-year-old man who experienced migraines with aura followed by epileptic seizures. The patient initially took topiramate, which reduced the frequency of migraines but did not fully control the seizures. The patient then switched to lamotrigine, which significantly improved both the migraines and seizures. The letter suggests that lamotrigine may be more effective in reducing seizure frequency by targeting the mechanisms underlying cortical spreading depression. Further studies are needed to better understand migralepsy. [Extracted from the article] |
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| Database: | Psychology and Behavioral Sciences Collection |
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| Abstract: | This letter discusses the relationship between migraine and epilepsy, specifically a condition called migralepsy. Migralepsy is characterized by a seizure that occurs during or within one hour after a migraine with aura. The letter describes a case of a 22-year-old man who experienced migraines with aura followed by epileptic seizures. The patient initially took topiramate, which reduced the frequency of migraines but did not fully control the seizures. The patient then switched to lamotrigine, which significantly improved both the migraines and seizures. The letter suggests that lamotrigine may be more effective in reducing seizure frequency by targeting the mechanisms underlying cortical spreading depression. Further studies are needed to better understand migralepsy. [Extracted from the article] |
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| ISSN: | 15901874 |
| DOI: | 10.1007/s10072-023-07291-w |
