Aging.
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| Title: | Aging. |
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| Authors: | Persson, Pontus B. (AUTHOR), Hillmeister, Philipp (AUTHOR), Buschmann, Ivo (AUTHOR), Bondke Persson, Anja (AUTHOR) |
| Source: | Acta Physiologica. Sep2024, Vol. 240 Issue 9, p1-3. 3p. |
| Subjects: | Human life cycle, Molecular biology, Cellular aging, Cardiovascular development, Exercise physiology, Endothelium diseases |
| Abstract: | This article provides a comprehensive overview of the aging process and its impact on human health. It explores the physical effects of aging, such as the deterioration of hearing, vision, muscles, bones, and joints, as well as the increased susceptibility to diseases. The article also discusses the differences in aging among animal species and the potential for humans to achieve extreme longevity and regeneration. It highlights recent breakthroughs in aging research, including the understanding of cellular mechanisms and the potential for therapeutic strategies. The article also examines the commonalities between degenerative diseases and the role of physical exercise in preventing and treating age-related diseases. It further explores the mechanisms of aging, such as genomic instability, telomere attrition, epigenetic alterations, loss of proteostasis, and mitochondrial dysfunction. The article emphasizes the importance of endothelial function in cardiovascular health and the potential of lifestyle changes and exercise in promoting healthy vascular aging. It concludes by discussing recent advances in aging research, including genetic and molecular breakthroughs, and the potential for translating these findings into clinical applications to improve the quality of life for the aging population. [Extracted from the article] |
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| Database: | Psychology and Behavioral Sciences Collection |
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| Abstract: | This article provides a comprehensive overview of the aging process and its impact on human health. It explores the physical effects of aging, such as the deterioration of hearing, vision, muscles, bones, and joints, as well as the increased susceptibility to diseases. The article also discusses the differences in aging among animal species and the potential for humans to achieve extreme longevity and regeneration. It highlights recent breakthroughs in aging research, including the understanding of cellular mechanisms and the potential for therapeutic strategies. The article also examines the commonalities between degenerative diseases and the role of physical exercise in preventing and treating age-related diseases. It further explores the mechanisms of aging, such as genomic instability, telomere attrition, epigenetic alterations, loss of proteostasis, and mitochondrial dysfunction. The article emphasizes the importance of endothelial function in cardiovascular health and the potential of lifestyle changes and exercise in promoting healthy vascular aging. It concludes by discussing recent advances in aging research, including genetic and molecular breakthroughs, and the potential for translating these findings into clinical applications to improve the quality of life for the aging population. [Extracted from the article] |
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| ISSN: | 17481708 |
| DOI: | 10.1111/apha.14192 |
