Who wants long-Acting injectable antiretroviral therapy? Treatment preferences among adults with HIV in Florida.

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Title: Who wants long-Acting injectable antiretroviral therapy? Treatment preferences among adults with HIV in Florida.
Authors: Fisk-Hoffman, Rebecca J., Liu, Yiyang, Somboonwit, Charurut, Widmeyer, Maya, Canidate, Shantrel, Prosperi, Mattia, Cook, Robert L.
Source: AIDS Care. Nov2024, Vol. 36 Issue 11, p1545-1554. 10p.
Subjects: Cross-sectional method, Patient compliance, Antiretroviral agents, Research funding, Secondary analysis, Income, Questionnaires, Logistic regression analysis, HIV infections, Descriptive statistics, Injections, Psychology of HIV-positive persons, Transportation, Dosage forms of drugs, Social networks, Genetic techniques, Confidence intervals, Drugs, Patients' attitudes
Geographic Terms: Florida
Abstract: Long-acting injectable (LAI) antiretroviral therapy (ART) is available to people with HIV (PWH), but it is unknown which PWH prefer this option. Using the Andersen Behavioral Model this study identifies characteristics of PWH with greater preference for LAI ART. Cross-sectional data from the Florida Cohort, which enrolled adult PWH from community-based clinics included information on predisposing (demographics), enabling (transportation, income), and need (ART adherence <90%) factors. ART preference was assessed via a single question (prefer pills, quarterly LAI, or no preference). Confounder-adjusted multinomial logistic regressions compared those who preferred pills to the other preference options, with covariates identified using directed acyclic graphs. Overall, 314 participants responded (40% non-Hispanic Black, 62% assigned male, 63% aged 50+). Most (63%) preferred the hypothetical LAI, 23% preferred pills, and 14% had no preference. PWH with access to a car (aRRR 1.97 95%CI 1.05–3.71), higher income (aRRR 2.55 95%CI 1.04–6.25), and suboptimal ART adherence (aRRR 7.41 95% CI 1.52–36.23) were more likely to prefer the LAI, while those who reported having no social network were less likely to prefer the LAI (aRRR 0.32 95% CI 0.11–0.88). Overall LAI interest was high, with greater preference associated with enabling and need factors. [ABSTRACT FROM AUTHOR]
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  Data: Who wants long-Acting injectable antiretroviral therapy? Treatment preferences among adults with HIV in Florida.
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  Data: &lt;searchLink fieldCode=&quot;JN&quot; term=&quot;%22AIDS+Care%22&quot;&gt;AIDS Care&lt;/searchLink&gt;. Nov2024, Vol. 36 Issue 11, p1545-1554. 10p.
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  Data: Long-acting injectable (LAI) antiretroviral therapy (ART) is available to people with HIV (PWH), but it is unknown which PWH prefer this option. Using the Andersen Behavioral Model this study identifies characteristics of PWH with greater preference for LAI ART. Cross-sectional data from the Florida Cohort, which enrolled adult PWH from community-based clinics included information on predisposing (demographics), enabling (transportation, income), and need (ART adherence &lt;90%) factors. ART preference was assessed via a single question (prefer pills, quarterly LAI, or no preference). Confounder-adjusted multinomial logistic regressions compared those who preferred pills to the other preference options, with covariates identified using directed acyclic graphs. Overall, 314 participants responded (40% non-Hispanic Black, 62% assigned male, 63% aged 50+). Most (63%) preferred the hypothetical LAI, 23% preferred pills, and 14% had no preference. PWH with access to a car (aRRR 1.97 95%CI 1.05–3.71), higher income (aRRR 2.55 95%CI 1.04–6.25), and suboptimal ART adherence (aRRR 7.41 95% CI 1.52–36.23) were more likely to prefer the LAI, while those who reported having no social network were less likely to prefer the LAI (aRRR 0.32 95% CI 0.11–0.88). Overall LAI interest was high, with greater preference associated with enabling and need factors. [ABSTRACT FROM AUTHOR]
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  Data: &lt;i&gt;Copyright of AIDS Care is the property of Taylor &amp; Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder&#39;s express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.&lt;/i&gt; (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1080/09540121.2024.2383872
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 10
        StartPage: 1545
    Subjects:
      – SubjectFull: Cross-sectional method
        Type: general
      – SubjectFull: Patient compliance
        Type: general
      – SubjectFull: Antiretroviral agents
        Type: general
      – SubjectFull: Research funding
        Type: general
      – SubjectFull: Secondary analysis
        Type: general
      – SubjectFull: Income
        Type: general
      – SubjectFull: Questionnaires
        Type: general
      – SubjectFull: Logistic regression analysis
        Type: general
      – SubjectFull: HIV infections
        Type: general
      – SubjectFull: Descriptive statistics
        Type: general
      – SubjectFull: Injections
        Type: general
      – SubjectFull: Psychology of HIV-positive persons
        Type: general
      – SubjectFull: Transportation
        Type: general
      – SubjectFull: Dosage forms of drugs
        Type: general
      – SubjectFull: Social networks
        Type: general
      – SubjectFull: Genetic techniques
        Type: general
      – SubjectFull: Confidence intervals
        Type: general
      – SubjectFull: Drugs
        Type: general
      – SubjectFull: Patients' attitudes
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      – SubjectFull: Florida
        Type: general
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      – TitleFull: Who wants long-Acting injectable antiretroviral therapy? Treatment preferences among adults with HIV in Florida.
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            – D: 01
              M: 11
              Text: Nov2024
              Type: published
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