Who wants long-Acting injectable antiretroviral therapy? Treatment preferences among adults with HIV in Florida.
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| Title: | Who wants long-Acting injectable antiretroviral therapy? Treatment preferences among adults with HIV in Florida. |
|---|---|
| Authors: | Fisk-Hoffman, Rebecca J., Liu, Yiyang, Somboonwit, Charurut, Widmeyer, Maya, Canidate, Shantrel, Prosperi, Mattia, Cook, Robert L. |
| Source: | AIDS Care. Nov2024, Vol. 36 Issue 11, p1545-1554. 10p. |
| Subjects: | Cross-sectional method, Patient compliance, Antiretroviral agents, Research funding, Secondary analysis, Income, Questionnaires, Logistic regression analysis, HIV infections, Descriptive statistics, Injections, Psychology of HIV-positive persons, Transportation, Dosage forms of drugs, Social networks, Genetic techniques, Confidence intervals, Drugs, Patients' attitudes |
| Geographic Terms: | Florida |
| Abstract: | Long-acting injectable (LAI) antiretroviral therapy (ART) is available to people with HIV (PWH), but it is unknown which PWH prefer this option. Using the Andersen Behavioral Model this study identifies characteristics of PWH with greater preference for LAI ART. Cross-sectional data from the Florida Cohort, which enrolled adult PWH from community-based clinics included information on predisposing (demographics), enabling (transportation, income), and need (ART adherence <90%) factors. ART preference was assessed via a single question (prefer pills, quarterly LAI, or no preference). Confounder-adjusted multinomial logistic regressions compared those who preferred pills to the other preference options, with covariates identified using directed acyclic graphs. Overall, 314 participants responded (40% non-Hispanic Black, 62% assigned male, 63% aged 50+). Most (63%) preferred the hypothetical LAI, 23% preferred pills, and 14% had no preference. PWH with access to a car (aRRR 1.97 95%CI 1.05–3.71), higher income (aRRR 2.55 95%CI 1.04–6.25), and suboptimal ART adherence (aRRR 7.41 95% CI 1.52–36.23) were more likely to prefer the LAI, while those who reported having no social network were less likely to prefer the LAI (aRRR 0.32 95% CI 0.11–0.88). Overall LAI interest was high, with greater preference associated with enabling and need factors. [ABSTRACT FROM AUTHOR] |
| Copyright of AIDS Care is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
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| Header | DbId: pbh DbLabel: Psychology and Behavioral Sciences Collection An: 180490260 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Who wants long-Acting injectable antiretroviral therapy? Treatment preferences among adults with HIV in Florida. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Fisk-Hoffman%2C+Rebecca+J%2E%22">Fisk-Hoffman, Rebecca J.</searchLink><br /><searchLink fieldCode="AR" term="%22Liu%2C+Yiyang%22">Liu, Yiyang</searchLink><br /><searchLink fieldCode="AR" term="%22Somboonwit%2C+Charurut%22">Somboonwit, Charurut</searchLink><br /><searchLink fieldCode="AR" term="%22Widmeyer%2C+Maya%22">Widmeyer, Maya</searchLink><br /><searchLink fieldCode="AR" term="%22Canidate%2C+Shantrel%22">Canidate, Shantrel</searchLink><br /><searchLink fieldCode="AR" term="%22Prosperi%2C+Mattia%22">Prosperi, Mattia</searchLink><br /><searchLink fieldCode="AR" term="%22Cook%2C+Robert+L%2E%22">Cook, Robert L.</searchLink> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22AIDS+Care%22">AIDS Care</searchLink>. Nov2024, Vol. 36 Issue 11, p1545-1554. 10p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Cross-sectional+method%22">Cross-sectional method</searchLink><br /><searchLink fieldCode="DE" term="%22Patient+compliance%22">Patient compliance</searchLink><br /><searchLink fieldCode="DE" term="%22Antiretroviral+agents%22">Antiretroviral agents</searchLink><br /><searchLink fieldCode="DE" term="%22Research+funding%22">Research funding</searchLink><br /><searchLink fieldCode="DE" term="%22Secondary+analysis%22">Secondary analysis</searchLink><br /><searchLink fieldCode="DE" term="%22Income%22">Income</searchLink><br /><searchLink fieldCode="DE" term="%22Questionnaires%22">Questionnaires</searchLink><br /><searchLink fieldCode="DE" term="%22Logistic+regression+analysis%22">Logistic regression analysis</searchLink><br /><searchLink fieldCode="DE" term="%22HIV+infections%22">HIV infections</searchLink><br /><searchLink fieldCode="DE" term="%22Descriptive+statistics%22">Descriptive statistics</searchLink><br /><searchLink fieldCode="DE" term="%22Injections%22">Injections</searchLink><br /><searchLink fieldCode="DE" term="%22Psychology+of+HIV-positive+persons%22">Psychology of HIV-positive persons</searchLink><br /><searchLink fieldCode="DE" term="%22Transportation%22">Transportation</searchLink><br /><searchLink fieldCode="DE" term="%22Dosage+forms+of+drugs%22">Dosage forms of drugs</searchLink><br /><searchLink fieldCode="DE" term="%22Social+networks%22">Social networks</searchLink><br /><searchLink fieldCode="DE" term="%22Genetic+techniques%22">Genetic techniques</searchLink><br /><searchLink fieldCode="DE" term="%22Confidence+intervals%22">Confidence intervals</searchLink><br /><searchLink fieldCode="DE" term="%22Drugs%22">Drugs</searchLink><br /><searchLink fieldCode="DE" term="%22Patients'+attitudes%22">Patients' attitudes</searchLink> – Name: SubjectGeographic Label: Geographic Terms Group: Su Data: <searchLink fieldCode="DE" term="%22Florida%22">Florida</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Long-acting injectable (LAI) antiretroviral therapy (ART) is available to people with HIV (PWH), but it is unknown which PWH prefer this option. Using the Andersen Behavioral Model this study identifies characteristics of PWH with greater preference for LAI ART. Cross-sectional data from the Florida Cohort, which enrolled adult PWH from community-based clinics included information on predisposing (demographics), enabling (transportation, income), and need (ART adherence <90%) factors. ART preference was assessed via a single question (prefer pills, quarterly LAI, or no preference). Confounder-adjusted multinomial logistic regressions compared those who preferred pills to the other preference options, with covariates identified using directed acyclic graphs. Overall, 314 participants responded (40% non-Hispanic Black, 62% assigned male, 63% aged 50+). Most (63%) preferred the hypothetical LAI, 23% preferred pills, and 14% had no preference. PWH with access to a car (aRRR 1.97 95%CI 1.05–3.71), higher income (aRRR 2.55 95%CI 1.04–6.25), and suboptimal ART adherence (aRRR 7.41 95% CI 1.52–36.23) were more likely to prefer the LAI, while those who reported having no social network were less likely to prefer the LAI (aRRR 0.32 95% CI 0.11–0.88). Overall LAI interest was high, with greater preference associated with enabling and need factors. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of AIDS Care is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=180490260 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1080/09540121.2024.2383872 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 10 StartPage: 1545 Subjects: – SubjectFull: Cross-sectional method Type: general – SubjectFull: Patient compliance Type: general – SubjectFull: Antiretroviral agents Type: general – SubjectFull: Research funding Type: general – SubjectFull: Secondary analysis Type: general – SubjectFull: Income Type: general – SubjectFull: Questionnaires Type: general – SubjectFull: Logistic regression analysis Type: general – SubjectFull: HIV infections Type: general – SubjectFull: Descriptive statistics Type: general – SubjectFull: Injections Type: general – SubjectFull: Psychology of HIV-positive persons Type: general – SubjectFull: Transportation Type: general – SubjectFull: Dosage forms of drugs Type: general – SubjectFull: Social networks Type: general – SubjectFull: Genetic techniques Type: general – SubjectFull: Confidence intervals Type: general – SubjectFull: Drugs Type: general – SubjectFull: Patients' attitudes Type: general – SubjectFull: Florida Type: general Titles: – TitleFull: Who wants long-Acting injectable antiretroviral therapy? Treatment preferences among adults with HIV in Florida. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Fisk-Hoffman, Rebecca J. – PersonEntity: Name: NameFull: Liu, Yiyang – PersonEntity: Name: NameFull: Somboonwit, Charurut – PersonEntity: Name: NameFull: Widmeyer, Maya – PersonEntity: Name: NameFull: Canidate, Shantrel – PersonEntity: Name: NameFull: Prosperi, Mattia – PersonEntity: Name: NameFull: Cook, Robert L. IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 11 Text: Nov2024 Type: published Y: 2024 Identifiers: – Type: issn-print Value: 09540121 Numbering: – Type: volume Value: 36 – Type: issue Value: 11 Titles: – TitleFull: AIDS Care Type: main |
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