Commentary on Ezard et al.: Prescribed psychostimulant medications for methamphetamine use disorder – an urgent path forward.

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Bibliographic Details
Title: Commentary on Ezard et al.: Prescribed psychostimulant medications for methamphetamine use disorder – an urgent path forward.
Authors: Bisaga, Adam
Source: Addiction. Jul2025, Vol. 120 Issue 7, p1360-1362. 3p.
Subjects: Substance abuse, Combination drug therapy, Patient compliance, Methamphetamine, Patient safety, Central nervous system stimulants, Dose-effect relationship in pharmacology, Quality of life, Drugs
Abstract: The author discusses a study by N. Ezard and colleagues which showed that high-dose prescription amphetamines can have small but significant benefit for individuals with severe methamphetamine use. Topics include indication of a dose-response relationship, consistent with an agonist-type mechanism, a major hurdle in stimulant (methamphetamine or cocaine) use disorder (StUD) clinical trials, and significance of adopting a medication-based treatment for StUD.
Database: Psychology and Behavioral Sciences Collection
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Abstract:The author discusses a study by N. Ezard and colleagues which showed that high-dose prescription amphetamines can have small but significant benefit for individuals with severe methamphetamine use. Topics include indication of a dose-response relationship, consistent with an agonist-type mechanism, a major hurdle in stimulant (methamphetamine or cocaine) use disorder (StUD) clinical trials, and significance of adopting a medication-based treatment for StUD.
ISSN:09652140
DOI:10.1111/add.70058