Subfoveal choroidal thickness and axial length changes with orthokeratology in bilateral anisomyopia.
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| Title: | Subfoveal choroidal thickness and axial length changes with orthokeratology in bilateral anisomyopia. |
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| Authors: | Wang, Jianglan (AUTHOR), Vincent, Stephen J. (AUTHOR), Liu, Longqian (AUTHOR), Bian, Siyu (AUTHOR), Cho, Pauline (AUTHOR) |
| Source: | Ophthalmic & Physiological Optics. Jul2025, Vol. 45 Issue 5, p1049-1055. 7p. |
| Subjects: | Choroid, Orthokeratology, Longitudinal method, School children, Refractive errors, Myopia |
| Abstract: | Purpose: To investigate the change in subfoveal choroidal thickness (SFChT) in bilateral anisomyopic children undergoing orthokeratology (ortho‐k) over 2 years and the association with axial elongation (AE). Methods: SFChT, axial length and refractive data from 26 bilateral anisomyopic subjects (aged 7–12 years) who participated in a 2‐year prospective orthokeratology study were analysed using generalised estimating equations and linear mixed models. Results: SFChT in the more myopic eyes (MME) (at least 1.50 D more myopia than the fellow eye) became thicker (mean ± standard deviation change, 25 ± 20 μm) after 6 months of ortho‐k lens wear (p < 0.001) and remained stable thereafter (p ≥ 0.13), but no such change was observed in the less myopic eyes (LME) (p ≥ 0.07). Combining data from both eyes, the baseline SFChT and SFChT change after 2 years of ortho‐k treatment were associated with 2‐year AE [generalised estimating equation (accounting for the inclusion of both eyes): β = 0.002, p = 0.03 and β = −0.005, p < 0.001, respectively]. Conclusions: After 2 years of ortho‐k treatment, the increase in the SFChT occurred exclusively in the MME. Considering both eyes, greater SFChT thickening was associated with less eye growth. [ABSTRACT FROM AUTHOR] |
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| Database: | Psychology and Behavioral Sciences Collection |
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| Abstract: | Purpose: To investigate the change in subfoveal choroidal thickness (SFChT) in bilateral anisomyopic children undergoing orthokeratology (ortho‐k) over 2 years and the association with axial elongation (AE). Methods: SFChT, axial length and refractive data from 26 bilateral anisomyopic subjects (aged 7–12 years) who participated in a 2‐year prospective orthokeratology study were analysed using generalised estimating equations and linear mixed models. Results: SFChT in the more myopic eyes (MME) (at least 1.50 D more myopia than the fellow eye) became thicker (mean ± standard deviation change, 25 ± 20 μm) after 6 months of ortho‐k lens wear (p < 0.001) and remained stable thereafter (p ≥ 0.13), but no such change was observed in the less myopic eyes (LME) (p ≥ 0.07). Combining data from both eyes, the baseline SFChT and SFChT change after 2 years of ortho‐k treatment were associated with 2‐year AE [generalised estimating equation (accounting for the inclusion of both eyes): β = 0.002, p = 0.03 and β = −0.005, p < 0.001, respectively]. Conclusions: After 2 years of ortho‐k treatment, the increase in the SFChT occurred exclusively in the MME. Considering both eyes, greater SFChT thickening was associated with less eye growth. [ABSTRACT FROM AUTHOR] |
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| ISSN: | 02755408 |
| DOI: | 10.1111/opo.13503 |
