Subfoveal choroidal thickness and axial length changes with orthokeratology in bilateral anisomyopia.
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| Title: | Subfoveal choroidal thickness and axial length changes with orthokeratology in bilateral anisomyopia. |
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| Authors: | Wang, Jianglan (AUTHOR), Vincent, Stephen J. (AUTHOR), Liu, Longqian (AUTHOR), Bian, Siyu (AUTHOR), Cho, Pauline (AUTHOR) |
| Source: | Ophthalmic & Physiological Optics. Jul2025, Vol. 45 Issue 5, p1049-1055. 7p. |
| Subjects: | Choroid, Orthokeratology, Longitudinal method, School children, Refractive errors, Myopia |
| Abstract: | Purpose: To investigate the change in subfoveal choroidal thickness (SFChT) in bilateral anisomyopic children undergoing orthokeratology (ortho‐k) over 2 years and the association with axial elongation (AE). Methods: SFChT, axial length and refractive data from 26 bilateral anisomyopic subjects (aged 7–12 years) who participated in a 2‐year prospective orthokeratology study were analysed using generalised estimating equations and linear mixed models. Results: SFChT in the more myopic eyes (MME) (at least 1.50 D more myopia than the fellow eye) became thicker (mean ± standard deviation change, 25 ± 20 μm) after 6 months of ortho‐k lens wear (p < 0.001) and remained stable thereafter (p ≥ 0.13), but no such change was observed in the less myopic eyes (LME) (p ≥ 0.07). Combining data from both eyes, the baseline SFChT and SFChT change after 2 years of ortho‐k treatment were associated with 2‐year AE [generalised estimating equation (accounting for the inclusion of both eyes): β = 0.002, p = 0.03 and β = −0.005, p < 0.001, respectively]. Conclusions: After 2 years of ortho‐k treatment, the increase in the SFChT occurred exclusively in the MME. Considering both eyes, greater SFChT thickening was associated with less eye growth. [ABSTRACT FROM AUTHOR] |
| Copyright of Ophthalmic & Physiological Optics is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
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| Header | DbId: pbh DbLabel: Psychology and Behavioral Sciences Collection An: 185862847 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Subfoveal choroidal thickness and axial length changes with orthokeratology in bilateral anisomyopia. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Wang%2C+Jianglan%22">Wang, Jianglan</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Vincent%2C+Stephen+J%2E%22">Vincent, Stephen J.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Liu%2C+Longqian%22">Liu, Longqian</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Bian%2C+Siyu%22">Bian, Siyu</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Cho%2C+Pauline%22">Cho, Pauline</searchLink> (AUTHOR) – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Ophthalmic+%26+Physiological+Optics%22">Ophthalmic & Physiological Optics</searchLink>. Jul2025, Vol. 45 Issue 5, p1049-1055. 7p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Choroid%22">Choroid</searchLink><br /><searchLink fieldCode="DE" term="%22Orthokeratology%22">Orthokeratology</searchLink><br /><searchLink fieldCode="DE" term="%22Longitudinal+method%22">Longitudinal method</searchLink><br /><searchLink fieldCode="DE" term="%22School+children%22">School children</searchLink><br /><searchLink fieldCode="DE" term="%22Refractive+errors%22">Refractive errors</searchLink><br /><searchLink fieldCode="DE" term="%22Myopia%22">Myopia</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Purpose: To investigate the change in subfoveal choroidal thickness (SFChT) in bilateral anisomyopic children undergoing orthokeratology (ortho‐k) over 2 years and the association with axial elongation (AE). Methods: SFChT, axial length and refractive data from 26 bilateral anisomyopic subjects (aged 7–12 years) who participated in a 2‐year prospective orthokeratology study were analysed using generalised estimating equations and linear mixed models. Results: SFChT in the more myopic eyes (MME) (at least 1.50 D more myopia than the fellow eye) became thicker (mean ± standard deviation change, 25 ± 20 μm) after 6 months of ortho‐k lens wear (p < 0.001) and remained stable thereafter (p ≥ 0.13), but no such change was observed in the less myopic eyes (LME) (p ≥ 0.07). Combining data from both eyes, the baseline SFChT and SFChT change after 2 years of ortho‐k treatment were associated with 2‐year AE [generalised estimating equation (accounting for the inclusion of both eyes): β = 0.002, p = 0.03 and β = −0.005, p < 0.001, respectively]. Conclusions: After 2 years of ortho‐k treatment, the increase in the SFChT occurred exclusively in the MME. Considering both eyes, greater SFChT thickening was associated with less eye growth. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Ophthalmic & Physiological Optics is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1111/opo.13503 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 7 StartPage: 1049 Subjects: – SubjectFull: Choroid Type: general – SubjectFull: Orthokeratology Type: general – SubjectFull: Longitudinal method Type: general – SubjectFull: School children Type: general – SubjectFull: Refractive errors Type: general – SubjectFull: Myopia Type: general Titles: – TitleFull: Subfoveal choroidal thickness and axial length changes with orthokeratology in bilateral anisomyopia. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Wang, Jianglan – PersonEntity: Name: NameFull: Vincent, Stephen J. – PersonEntity: Name: NameFull: Liu, Longqian – PersonEntity: Name: NameFull: Bian, Siyu – PersonEntity: Name: NameFull: Cho, Pauline IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 07 Text: Jul2025 Type: published Y: 2025 Identifiers: – Type: issn-print Value: 02755408 Numbering: – Type: volume Value: 45 – Type: issue Value: 5 Titles: – TitleFull: Ophthalmic & Physiological Optics Type: main |
| ResultId | 1 |
