Continuous Electroencephalogram (cEEG) Findings and Neurodevelopmental Outcomes in Neonates with Congenital Heart Disease (CHD) at 12–24 Months of Age.
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| Title: | Continuous Electroencephalogram (cEEG) Findings and Neurodevelopmental Outcomes in Neonates with Congenital Heart Disease (CHD) at 12–24 Months of Age. |
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| Authors: | Padiyar, Swetha, Friedman, Neil, Pestana-Knight, Elia, Franic, Linda, Worley, Sarah, Aly, Hany |
| Source: | Journal of Autism & Developmental Disorders. Sep2025, Vol. 55 Issue 9, p3245-3256. 12p. |
| Subjects: | Prevention of surgical complications, Congenital heart disease, Risk assessment, Language & languages, Statistical correlation, Child psychopathology, Data analysis, Electroencephalography, Neural development, Neonatal intensive care units, Kruskal-Wallis Test, Cardiopulmonary bypass, Retrospective studies, Descriptive statistics, Preoperative care, Neonatal intensive care, Developmental disabilities, Longitudinal method, Pediatrics, Child development, Gestational age, Research, Intensive care units, Statistics, Surgical instruments, Postoperative period, Data analysis software, Cardiac surgery, Disease risk factors, Disease complications, Children |
| Geographic Terms: | Ohio |
| Abstract: | Objective: This study aims to assess the role of continuous EEG (cEEG) background patterns and duration of cross-clamp time and cardiopulmonary bypass (CPB) in children with congenital heart disease (CHD) undergoing cardiac surgery and its correlation with abnormal neurodevelopmental outcomes at 12–24 months on Bayley Scales of Infant and Toddler Development (BSID-III). Methods: This retrospective cohort study included infants with CHD and cEEG monitoring, who underwent surgery by 44 weeks gestational age. Results: 34 patients were included, who were operated at median age − 7 days. Longer duration of cross- camp time was associated with poor language composite scores (LCS) (p value = 0.036). A significant association existed between severity of encephalopathy in 24-hour post-operative period and poor LCS (p value = 0.026). Conclusion: Majority of neonates with CHD have below average cognitive, language and motor composite scores on BSID-III. Longer duration of cross-clamp time and severity of encephalopathy during 24-hour post-operative EEG monitoring are associated with poor LCS. [ABSTRACT FROM AUTHOR] |
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| Database: | Psychology and Behavioral Sciences Collection |
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| Abstract: | Objective: This study aims to assess the role of continuous EEG (cEEG) background patterns and duration of cross-clamp time and cardiopulmonary bypass (CPB) in children with congenital heart disease (CHD) undergoing cardiac surgery and its correlation with abnormal neurodevelopmental outcomes at 12–24 months on Bayley Scales of Infant and Toddler Development (BSID-III). Methods: This retrospective cohort study included infants with CHD and cEEG monitoring, who underwent surgery by 44 weeks gestational age. Results: 34 patients were included, who were operated at median age − 7 days. Longer duration of cross- camp time was associated with poor language composite scores (LCS) (p value = 0.036). A significant association existed between severity of encephalopathy in 24-hour post-operative period and poor LCS (p value = 0.026). Conclusion: Majority of neonates with CHD have below average cognitive, language and motor composite scores on BSID-III. Longer duration of cross-clamp time and severity of encephalopathy during 24-hour post-operative EEG monitoring are associated with poor LCS. [ABSTRACT FROM AUTHOR] |
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| ISSN: | 01623257 |
| DOI: | 10.1007/s10803-024-06418-y |
