Bats Are Natural Reservoirs of SARS-Like Coronaviruses.
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| Title: | Bats Are Natural Reservoirs of SARS-Like Coronaviruses. |
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| Authors: | Li, Wendong, Shi, Zhengli, Yu, Meng, Ren, Wuze, Smith, Craig, Epstein, Jonathan H., Wang, Hanzhong, Crameri, Gary, Hu, Zhihong, Zhang, Huajun, Zhang, Jianhong, McEachern, Jennifer, Field, Hume, Daszak, Peter, Eaton, Bryan T., Zhang, Shuyi, Wang, Lin-Fa |
| Source: | Science (pre-March 2025). 10/28/2005, Vol. 310 Issue 5748, p676-679. 4p. 3 Diagrams, 1 Chart. |
| Subjects: | Coronaviruses, SARS disease, Bats, RNA viruses, Phylogeny, Viruses |
| Abstract: | Severe acute respiratory syndrome (SARS) emerged in 2002 to 2003 in southern China. The origin of its etiological agent, the SARS coronavirus (SARS-CoV), remains elusive. Here we report that species of bats are a natural host of coronaviruses closely related to those responsible for the SARS outbreak. These viruses, termed SARS-like coronaviruses (SL-CoVs), display greater genetic variation than SARS-CoV isolated from humans or from civets. The human and civet isolates of SARS-CoV nestle phylogenetically within the spectrum of SL-CoVs, indicating that the virus responsible for the SARS outbreak was a member of this coronavirus group. [ABSTRACT FROM AUTHOR] |
| Copyright of Science (pre-March 2025) is the property of American Association for the Advancement of Science and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
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| Abstract: | Severe acute respiratory syndrome (SARS) emerged in 2002 to 2003 in southern China. The origin of its etiological agent, the SARS coronavirus (SARS-CoV), remains elusive. Here we report that species of bats are a natural host of coronaviruses closely related to those responsible for the SARS outbreak. These viruses, termed SARS-like coronaviruses (SL-CoVs), display greater genetic variation than SARS-CoV isolated from humans or from civets. The human and civet isolates of SARS-CoV nestle phylogenetically within the spectrum of SL-CoVs, indicating that the virus responsible for the SARS outbreak was a member of this coronavirus group. [ABSTRACT FROM AUTHOR] |
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| ISSN: | 00368075 |
