Adverse Birth Outcomes in Pregnant Women With Intellectual and/or Developmental Disabilities by Substance Use Disorder Status.
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| Title: | Adverse Birth Outcomes in Pregnant Women With Intellectual and/or Developmental Disabilities by Substance Use Disorder Status. |
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| Authors: | Kim, Jaewhan (AUTHOR), Taylor, Isabel K. (AUTHOR), Schwab, Tyson (AUTHOR), King, Camille (AUTHOR), Duru, Emeka Elvis (AUTHOR), Jones, Kyle Bradford (AUTHOR) |
| Source: | Substance Use & Misuse. 2025, Vol. 60 Issue 13, p2055-2062. 8p. |
| Subjects: | Substance abuse risk factors, Risk assessment, Cesarean section, Research funding, Human abnormalities, T-test (Statistics), Neonatal intensive care units, Premature infants, Logistic regression analysis, Pregnant women, Pregnancy outcomes, Retrospective studies, Neonatal intensive care, Descriptive statistics, Chi-squared test, Cerebral palsy, Intellectual disabilities, Developmental disabilities, Longitudinal method, Low birth weight, Prenatal care, Odds ratio, Medical records, Acquisition of data, Gestational age, Pregnancy complications, Comparative studies, Data analysis software, People with disabilities, Disease complications, Pregnancy |
| Geographic Terms: | Utah |
| Abstract: | Objective: There remains a gap in research examining substance use disorder (SUD) during pregnancy among women with intellectual and/or developmental disabilities (IDDs). This study investigates the association between SUD and birth outcomes in this population. Methods: This retrospective cohort study analyzed 5,512 births from 2,445 mothers with IDDs using the Utah Population Database (1996–2018). Outcomes included preterm birth, low birth weight, cesarean delivery, congenital anomalies, and neonatal intensive care unit (NICU) admission. Random-effects logistic regression models were applied. Results: Among all births, 18.8% were to mothers with SUD, with this rate increasing from 8% in 1996 to 48% in 2018. SUD was associated with a 57% higher risk of preterm birth (OR = 1.57, p = 0.01). Low birth weight was more common in the SUD group, with a 90% increased risk (OR = 1.90, p < 0.01). SUD was also linked to higher rates of cesarean delivery (OR = 2.22, p = 0.02), while it was not significantly associated with NICU admission (OR = 1.43, p = 0.11). Conclusions: This study reveals significant associations between SUD and adverse birth outcomes in pregnant individuals with IDDs. The findings underscore the need for targeted interventions to mitigate risks and improve access to prenatal care. [ABSTRACT FROM AUTHOR] |
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| Database: | Psychology and Behavioral Sciences Collection |
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| Abstract: | Objective: There remains a gap in research examining substance use disorder (SUD) during pregnancy among women with intellectual and/or developmental disabilities (IDDs). This study investigates the association between SUD and birth outcomes in this population. Methods: This retrospective cohort study analyzed 5,512 births from 2,445 mothers with IDDs using the Utah Population Database (1996–2018). Outcomes included preterm birth, low birth weight, cesarean delivery, congenital anomalies, and neonatal intensive care unit (NICU) admission. Random-effects logistic regression models were applied. Results: Among all births, 18.8% were to mothers with SUD, with this rate increasing from 8% in 1996 to 48% in 2018. SUD was associated with a 57% higher risk of preterm birth (OR = 1.57, p = 0.01). Low birth weight was more common in the SUD group, with a 90% increased risk (OR = 1.90, p < 0.01). SUD was also linked to higher rates of cesarean delivery (OR = 2.22, p = 0.02), while it was not significantly associated with NICU admission (OR = 1.43, p = 0.11). Conclusions: This study reveals significant associations between SUD and adverse birth outcomes in pregnant individuals with IDDs. The findings underscore the need for targeted interventions to mitigate risks and improve access to prenatal care. [ABSTRACT FROM AUTHOR] |
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| ISSN: | 10826084 |
| DOI: | 10.1080/10826084.2025.2533971 |
