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Adverse Birth Outcomes in Pregnant Women With Intellectual and/or Developmental Disabilities by Substance Use Disorder Status.

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Title: Adverse Birth Outcomes in Pregnant Women With Intellectual and/or Developmental Disabilities by Substance Use Disorder Status.
Authors: Kim, Jaewhan (AUTHOR), Taylor, Isabel K. (AUTHOR), Schwab, Tyson (AUTHOR), King, Camille (AUTHOR), Duru, Emeka Elvis (AUTHOR), Jones, Kyle Bradford (AUTHOR)
Source: Substance Use & Misuse. 2025, Vol. 60 Issue 13, p2055-2062. 8p.
Subjects: Substance abuse risk factors, Risk assessment, Cesarean section, Research funding, Human abnormalities, T-test (Statistics), Neonatal intensive care units, Premature infants, Logistic regression analysis, Pregnant women, Pregnancy outcomes, Retrospective studies, Neonatal intensive care, Descriptive statistics, Chi-squared test, Cerebral palsy, Intellectual disabilities, Developmental disabilities, Longitudinal method, Low birth weight, Prenatal care, Odds ratio, Medical records, Acquisition of data, Gestational age, Pregnancy complications, Comparative studies, Data analysis software, People with disabilities, Disease complications, Pregnancy
Geographic Terms: Utah
Abstract: Objective: There remains a gap in research examining substance use disorder (SUD) during pregnancy among women with intellectual and/or developmental disabilities (IDDs). This study investigates the association between SUD and birth outcomes in this population. Methods: This retrospective cohort study analyzed 5,512 births from 2,445 mothers with IDDs using the Utah Population Database (1996–2018). Outcomes included preterm birth, low birth weight, cesarean delivery, congenital anomalies, and neonatal intensive care unit (NICU) admission. Random-effects logistic regression models were applied. Results: Among all births, 18.8% were to mothers with SUD, with this rate increasing from 8% in 1996 to 48% in 2018. SUD was associated with a 57% higher risk of preterm birth (OR = 1.57, p = 0.01). Low birth weight was more common in the SUD group, with a 90% increased risk (OR = 1.90, p < 0.01). SUD was also linked to higher rates of cesarean delivery (OR = 2.22, p = 0.02), while it was not significantly associated with NICU admission (OR = 1.43, p = 0.11). Conclusions: This study reveals significant associations between SUD and adverse birth outcomes in pregnant individuals with IDDs. The findings underscore the need for targeted interventions to mitigate risks and improve access to prenatal care. [ABSTRACT FROM AUTHOR]
Copyright of Substance Use & Misuse is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: Adverse Birth Outcomes in Pregnant Women With Intellectual and/or Developmental Disabilities by Substance Use Disorder Status.
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  Data: Objective: There remains a gap in research examining substance use disorder (SUD) during pregnancy among women with intellectual and/or developmental disabilities (IDDs). This study investigates the association between SUD and birth outcomes in this population. Methods: This retrospective cohort study analyzed 5,512 births from 2,445 mothers with IDDs using the Utah Population Database (1996–2018). Outcomes included preterm birth, low birth weight, cesarean delivery, congenital anomalies, and neonatal intensive care unit (NICU) admission. Random-effects logistic regression models were applied. Results: Among all births, 18.8% were to mothers with SUD, with this rate increasing from 8% in 1996 to 48% in 2018. SUD was associated with a 57% higher risk of preterm birth (OR = 1.57, p = 0.01). Low birth weight was more common in the SUD group, with a 90% increased risk (OR = 1.90, p &lt; 0.01). SUD was also linked to higher rates of cesarean delivery (OR = 2.22, p = 0.02), while it was not significantly associated with NICU admission (OR = 1.43, p = 0.11). Conclusions: This study reveals significant associations between SUD and adverse birth outcomes in pregnant individuals with IDDs. The findings underscore the need for targeted interventions to mitigate risks and improve access to prenatal care. [ABSTRACT FROM AUTHOR]
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  Data: &lt;i&gt;Copyright of Substance Use &amp; Misuse is the property of Taylor &amp; Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder&#39;s express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.&lt;/i&gt; (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=188496395
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1080/10826084.2025.2533971
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 8
        StartPage: 2055
    Subjects:
      – SubjectFull: Substance abuse risk factors
        Type: general
      – SubjectFull: Risk assessment
        Type: general
      – SubjectFull: Cesarean section
        Type: general
      – SubjectFull: Research funding
        Type: general
      – SubjectFull: Human abnormalities
        Type: general
      – SubjectFull: T-test (Statistics)
        Type: general
      – SubjectFull: Neonatal intensive care units
        Type: general
      – SubjectFull: Premature infants
        Type: general
      – SubjectFull: Logistic regression analysis
        Type: general
      – SubjectFull: Pregnant women
        Type: general
      – SubjectFull: Pregnancy outcomes
        Type: general
      – SubjectFull: Retrospective studies
        Type: general
      – SubjectFull: Neonatal intensive care
        Type: general
      – SubjectFull: Descriptive statistics
        Type: general
      – SubjectFull: Chi-squared test
        Type: general
      – SubjectFull: Cerebral palsy
        Type: general
      – SubjectFull: Intellectual disabilities
        Type: general
      – SubjectFull: Developmental disabilities
        Type: general
      – SubjectFull: Longitudinal method
        Type: general
      – SubjectFull: Low birth weight
        Type: general
      – SubjectFull: Prenatal care
        Type: general
      – SubjectFull: Odds ratio
        Type: general
      – SubjectFull: Medical records
        Type: general
      – SubjectFull: Acquisition of data
        Type: general
      – SubjectFull: Gestational age
        Type: general
      – SubjectFull: Pregnancy complications
        Type: general
      – SubjectFull: Comparative studies
        Type: general
      – SubjectFull: Data analysis software
        Type: general
      – SubjectFull: People with disabilities
        Type: general
      – SubjectFull: Disease complications
        Type: general
      – SubjectFull: Pregnancy
        Type: general
      – SubjectFull: Utah
        Type: general
    Titles:
      – TitleFull: Adverse Birth Outcomes in Pregnant Women With Intellectual and/or Developmental Disabilities by Substance Use Disorder Status.
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              Text: 2025
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