Changes in physical activity 1 year after breast cancer diagnosis and associations with patient-reported outcomes: results from the AMBER cohort.
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| Title: | Changes in physical activity 1 year after breast cancer diagnosis and associations with patient-reported outcomes: results from the AMBER cohort. |
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| Authors: | Vallance, Jeff (AUTHOR), Friedenreich, Christine (AUTHOR), Zhang, Ruixuan (AUTHOR), Wang, Qinggang (AUTHOR), Matthews, Charles (AUTHOR), Yang, Lin (AUTHOR), McNeely, Margaret (AUTHOR), Wagoner, Chad (AUTHOR), Culos-Reed, Nicole (AUTHOR), Bell, Gordon (AUTHOR) |
| Source: | Annals of Behavioral Medicine. Jan2025, Vol. 59 Issue 1, p1-11. 11p. |
| Subjects: | Physical activity, Patient reported outcome measures, Cohort analysis, Quality of life, Fatigue (Physiology), Mental health, Breast tumors, Accelerometers |
| Abstract: | Background Few studies have prospectively examined how changes in physical activity in the first year after a breast cancer diagnosis may affect patient-reported outcomes (PROs) including quality of life and fatigue. Purpose The purpose of this study was to examine changes in device-measured physical activity and associations with changes in quality of life [physical composite summary score (PCS) and mental composite summary score (MCS)] and fatigue from the first year after diagnosis among newly diagnosed women with breast cancer in the Alberta Moving Beyond Breast Cancer Study. Methods In this prospective cohort study, we assessed women within a median of 60 days postsurgery (N = 1442) and again 1 year later (N = 1194). At both timepoints, participants wore an ActiGraph accelerometer for 7 days to measure light and moderate-to-vigorous physical activity (MVPA) and an activPAL accelerometer for daily steps. We used analysis of covariance to compare PRO change scores (dependent variables: PCS and MCS, and fatigue) across activity change quartiles (Q). Results Participants were categorized into Q1 (decreased activity: mean changes = −37.2 minutes/day), Q2 (stable activity: mean change = −4.8 minutes/day), Q3 (modest increase in activity: mean change = 13.2 minutes/day), and Q4 (large increase in activity: mean change = +49.8 minutes/day). For MVPA, participants in Q4 had significantly larger improvements in PCS and MCS compared with those in the lowest quartiles (PCS: Q1 Δ = 1.5 points, P =.026; Q2 Δ = 1.6 points, P =.017; MCS: Q1 Δ = 2.2 points, P =.007). Significant differences also emerged for fatigue as participants in Q4 of MVPA reported improvements in fatigue compared to those in Q1 (Δ = 1.9 points, P =.017) and Q2 (Δ = 1.9 points, P =.016). Improvements in PCS, MCS, and fatigue were observed when comparing the highest quartile of change (Q4) in light intensity activity, daily steps, and MVPA in ≥10-minute bouts to those in Q1 and Q2. Conclusions Women with breast cancer who increased physical activity from diagnosis to 1 year had significantly better improvements in PCS, MCS, and fatigue compared with those who decreased or maintained their physical activity. [ABSTRACT FROM AUTHOR] |
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| Database: | Psychology and Behavioral Sciences Collection |
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| Abstract: | Background Few studies have prospectively examined how changes in physical activity in the first year after a breast cancer diagnosis may affect patient-reported outcomes (PROs) including quality of life and fatigue. Purpose The purpose of this study was to examine changes in device-measured physical activity and associations with changes in quality of life [physical composite summary score (PCS) and mental composite summary score (MCS)] and fatigue from the first year after diagnosis among newly diagnosed women with breast cancer in the Alberta Moving Beyond Breast Cancer Study. Methods In this prospective cohort study, we assessed women within a median of 60 days postsurgery (N = 1442) and again 1 year later (N = 1194). At both timepoints, participants wore an ActiGraph accelerometer for 7 days to measure light and moderate-to-vigorous physical activity (MVPA) and an activPAL accelerometer for daily steps. We used analysis of covariance to compare PRO change scores (dependent variables: PCS and MCS, and fatigue) across activity change quartiles (Q). Results Participants were categorized into Q1 (decreased activity: mean changes = −37.2 minutes/day), Q2 (stable activity: mean change = −4.8 minutes/day), Q3 (modest increase in activity: mean change = 13.2 minutes/day), and Q4 (large increase in activity: mean change = +49.8 minutes/day). For MVPA, participants in Q4 had significantly larger improvements in PCS and MCS compared with those in the lowest quartiles (PCS: Q1 Δ = 1.5 points, P =.026; Q2 Δ = 1.6 points, P =.017; MCS: Q1 Δ = 2.2 points, P =.007). Significant differences also emerged for fatigue as participants in Q4 of MVPA reported improvements in fatigue compared to those in Q1 (Δ = 1.9 points, P =.017) and Q2 (Δ = 1.9 points, P =.016). Improvements in PCS, MCS, and fatigue were observed when comparing the highest quartile of change (Q4) in light intensity activity, daily steps, and MVPA in ≥10-minute bouts to those in Q1 and Q2. Conclusions Women with breast cancer who increased physical activity from diagnosis to 1 year had significantly better improvements in PCS, MCS, and fatigue compared with those who decreased or maintained their physical activity. [ABSTRACT FROM AUTHOR] |
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| ISSN: | 08836612 |
| DOI: | 10.1093/abm/kaaf098 |
