Methamphetamine Use, Post-Traumatic Stress, and Substance Use Consequences Among American Indians with a Substance Use Problem.
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| Title: | Methamphetamine Use, Post-Traumatic Stress, and Substance Use Consequences Among American Indians with a Substance Use Problem. |
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| Authors: | Skewes, Monica C. (AUTHOR), Anastario, Michael (AUTHOR) |
| Source: | Substance Use & Misuse. 2026, Vol. 61 Issue 8, p1153-1161. 9p. |
| Subjects: | Complications of alcoholism, Post-traumatic stress disorder, Substance abuse, Cross-sectional method, Medical care research, Poisson distribution, Methamphetamine, Research funding, Questionnaires, Probability theory, Descriptive statistics, Social responsibility, Families, Odds ratio, Impulse control disorders, Confidence intervals, Data analysis software, Interpersonal relations, Psychology of Native Americans, Regression analysis, Disease complications |
| Abstract: | Objective: This manuscript explores the relationship between methamphetamine as the primary drug of choice, symptoms of posttraumatic stress disorder (PTSD), and adverse consequences of alcohol/drug use in a sample of American Indian (AI) people who self-identified as having a current substance use problem. Method: Using a Community-Based Participatory Research framework, we conducted a cross-sectional survey with 198 AI tribal members experiencing addiction. In the analyses, substance use-related adverse consequences in the lifetime and past 30 days served as outcome variables. Results: Using Bayesian models, we found greater consequences for people who reported methamphetamine as their primary drug of choice as compared to those who reported other primary drugs. Moreover, PTSD symptoms were associated with increased substance use consequences across a variety of domains, regardless of primary drug used. Appreciable interaction effects were detected between methamphetamine as the primary drug of choice and PTSD symptoms for lifetime interpersonal, intrapersonal, impulse control, social responsibility, and kinship loss consequences. While methamphetamine use was associated with greater lifetime interpersonal consequences, the association between PTSD symptoms and consequences was weaker among those who used methamphetamine as their primary drug. Conclusion: Tribal members who report methamphetamine as their primary drug and those who have higher PTSD scores experience significant substance use consequences. Interventions that address stimulant use and traumatic stress are needed to improve health outcomes in this population. PUBLIC HEALTH SIGNIFICANCE: This study reports findings from a Community-Based Participatory Research project that took place on an American Indian reservation with tribal members who identified as having a current substance use problem. Findings showed greater substance use consequences among participants who reported using methamphetamine as their primary drug and among those with greater trauma symptoms. This study highlights the importance of developing culturally relevant interventions to treat methamphetamine use disorder and post-traumatic stress disorder among American Indian people. [ABSTRACT FROM AUTHOR] |
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| Database: | Psychology and Behavioral Sciences Collection |
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| Abstract: | Objective: This manuscript explores the relationship between methamphetamine as the primary drug of choice, symptoms of posttraumatic stress disorder (PTSD), and adverse consequences of alcohol/drug use in a sample of American Indian (AI) people who self-identified as having a current substance use problem. Method: Using a Community-Based Participatory Research framework, we conducted a cross-sectional survey with 198 AI tribal members experiencing addiction. In the analyses, substance use-related adverse consequences in the lifetime and past 30 days served as outcome variables. Results: Using Bayesian models, we found greater consequences for people who reported methamphetamine as their primary drug of choice as compared to those who reported other primary drugs. Moreover, PTSD symptoms were associated with increased substance use consequences across a variety of domains, regardless of primary drug used. Appreciable interaction effects were detected between methamphetamine as the primary drug of choice and PTSD symptoms for lifetime interpersonal, intrapersonal, impulse control, social responsibility, and kinship loss consequences. While methamphetamine use was associated with greater lifetime interpersonal consequences, the association between PTSD symptoms and consequences was weaker among those who used methamphetamine as their primary drug. Conclusion: Tribal members who report methamphetamine as their primary drug and those who have higher PTSD scores experience significant substance use consequences. Interventions that address stimulant use and traumatic stress are needed to improve health outcomes in this population. PUBLIC HEALTH SIGNIFICANCE: This study reports findings from a Community-Based Participatory Research project that took place on an American Indian reservation with tribal members who identified as having a current substance use problem. Findings showed greater substance use consequences among participants who reported using methamphetamine as their primary drug and among those with greater trauma symptoms. This study highlights the importance of developing culturally relevant interventions to treat methamphetamine use disorder and post-traumatic stress disorder among American Indian people. [ABSTRACT FROM AUTHOR] |
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| ISSN: | 10826084 |
| DOI: | 10.1080/10826084.2025.2598403 |