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Methamphetamine Use, Post-Traumatic Stress, and Substance Use Consequences Among American Indians with a Substance Use Problem.

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Title: Methamphetamine Use, Post-Traumatic Stress, and Substance Use Consequences Among American Indians with a Substance Use Problem.
Authors: Skewes, Monica C. (AUTHOR), Anastario, Michael (AUTHOR)
Source: Substance Use & Misuse. 2026, Vol. 61 Issue 8, p1153-1161. 9p.
Subjects: Complications of alcoholism, Post-traumatic stress disorder, Substance abuse, Cross-sectional method, Medical care research, Poisson distribution, Methamphetamine, Research funding, Questionnaires, Probability theory, Descriptive statistics, Social responsibility, Families, Odds ratio, Impulse control disorders, Confidence intervals, Data analysis software, Interpersonal relations, Psychology of Native Americans, Regression analysis, Disease complications
Abstract: Objective: This manuscript explores the relationship between methamphetamine as the primary drug of choice, symptoms of posttraumatic stress disorder (PTSD), and adverse consequences of alcohol/drug use in a sample of American Indian (AI) people who self-identified as having a current substance use problem. Method: Using a Community-Based Participatory Research framework, we conducted a cross-sectional survey with 198 AI tribal members experiencing addiction. In the analyses, substance use-related adverse consequences in the lifetime and past 30 days served as outcome variables. Results: Using Bayesian models, we found greater consequences for people who reported methamphetamine as their primary drug of choice as compared to those who reported other primary drugs. Moreover, PTSD symptoms were associated with increased substance use consequences across a variety of domains, regardless of primary drug used. Appreciable interaction effects were detected between methamphetamine as the primary drug of choice and PTSD symptoms for lifetime interpersonal, intrapersonal, impulse control, social responsibility, and kinship loss consequences. While methamphetamine use was associated with greater lifetime interpersonal consequences, the association between PTSD symptoms and consequences was weaker among those who used methamphetamine as their primary drug. Conclusion: Tribal members who report methamphetamine as their primary drug and those who have higher PTSD scores experience significant substance use consequences. Interventions that address stimulant use and traumatic stress are needed to improve health outcomes in this population. PUBLIC HEALTH SIGNIFICANCE: This study reports findings from a Community-Based Participatory Research project that took place on an American Indian reservation with tribal members who identified as having a current substance use problem. Findings showed greater substance use consequences among participants who reported using methamphetamine as their primary drug and among those with greater trauma symptoms. This study highlights the importance of developing culturally relevant interventions to treat methamphetamine use disorder and post-traumatic stress disorder among American Indian people. [ABSTRACT FROM AUTHOR]
Copyright of Substance Use & Misuse is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: Methamphetamine Use, Post-Traumatic Stress, and Substance Use Consequences Among American Indians with a Substance Use Problem.
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  Data: <searchLink fieldCode="JN" term="%22Substance+Use+%26+Misuse%22">Substance Use & Misuse</searchLink>. 2026, Vol. 61 Issue 8, p1153-1161. 9p.
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– Name: Abstract
  Label: Abstract
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  Data: Objective: This manuscript explores the relationship between methamphetamine as the primary drug of choice, symptoms of posttraumatic stress disorder (PTSD), and adverse consequences of alcohol/drug use in a sample of American Indian (AI) people who self-identified as having a current substance use problem. Method: Using a Community-Based Participatory Research framework, we conducted a cross-sectional survey with 198 AI tribal members experiencing addiction. In the analyses, substance use-related adverse consequences in the lifetime and past 30 days served as outcome variables. Results: Using Bayesian models, we found greater consequences for people who reported methamphetamine as their primary drug of choice as compared to those who reported other primary drugs. Moreover, PTSD symptoms were associated with increased substance use consequences across a variety of domains, regardless of primary drug used. Appreciable interaction effects were detected between methamphetamine as the primary drug of choice and PTSD symptoms for lifetime interpersonal, intrapersonal, impulse control, social responsibility, and kinship loss consequences. While methamphetamine use was associated with greater lifetime interpersonal consequences, the association between PTSD symptoms and consequences was weaker among those who used methamphetamine as their primary drug. Conclusion: Tribal members who report methamphetamine as their primary drug and those who have higher PTSD scores experience significant substance use consequences. Interventions that address stimulant use and traumatic stress are needed to improve health outcomes in this population. PUBLIC HEALTH SIGNIFICANCE: This study reports findings from a Community-Based Participatory Research project that took place on an American Indian reservation with tribal members who identified as having a current substance use problem. Findings showed greater substance use consequences among participants who reported using methamphetamine as their primary drug and among those with greater trauma symptoms. This study highlights the importance of developing culturally relevant interventions to treat methamphetamine use disorder and post-traumatic stress disorder among American Indian people. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Substance Use & Misuse is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=193623152
RecordInfo BibRecord:
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    Identifiers:
      – Type: doi
        Value: 10.1080/10826084.2025.2598403
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 9
        StartPage: 1153
    Subjects:
      – SubjectFull: Complications of alcoholism
        Type: general
      – SubjectFull: Post-traumatic stress disorder
        Type: general
      – SubjectFull: Substance abuse
        Type: general
      – SubjectFull: Cross-sectional method
        Type: general
      – SubjectFull: Medical care research
        Type: general
      – SubjectFull: Poisson distribution
        Type: general
      – SubjectFull: Methamphetamine
        Type: general
      – SubjectFull: Research funding
        Type: general
      – SubjectFull: Questionnaires
        Type: general
      – SubjectFull: Probability theory
        Type: general
      – SubjectFull: Descriptive statistics
        Type: general
      – SubjectFull: Social responsibility
        Type: general
      – SubjectFull: Families
        Type: general
      – SubjectFull: Odds ratio
        Type: general
      – SubjectFull: Impulse control disorders
        Type: general
      – SubjectFull: Confidence intervals
        Type: general
      – SubjectFull: Data analysis software
        Type: general
      – SubjectFull: Interpersonal relations
        Type: general
      – SubjectFull: Psychology of Native Americans
        Type: general
      – SubjectFull: Regression analysis
        Type: general
      – SubjectFull: Disease complications
        Type: general
    Titles:
      – TitleFull: Methamphetamine Use, Post-Traumatic Stress, and Substance Use Consequences Among American Indians with a Substance Use Problem.
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            NameFull: Skewes, Monica C.
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            NameFull: Anastario, Michael
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            – D: 01
              M: 07
              Text: 2026
              Type: published
              Y: 2026
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              Value: 61
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            – TitleFull: Substance Use & Misuse
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