Bibliographic Details
| Title: |
Risk of major psychiatric disorder after adolescent pregnancy: A nationwide cohort study of 149,870 girls. |
| Authors: |
Hsu, Tien‐Wei (AUTHOR), Li, Jia‐Ru (AUTHOR), Tsai, Shih‐Jen (AUTHOR), Bai, Ya‐Mei (AUTHOR), Su, Tung‐Ping (AUTHOR), Chen, Tzeng‐Ji (AUTHOR), Hsu, Ju‐Wei (AUTHOR), Chen, Mu‐Hong (AUTHOR), Liang, Chih‐Sung (AUTHOR) |
| Source: |
Psychiatry & Clinical Neurosciences. Jun2026, Vol. 80 Issue 6, p519-526. 8p. |
| Subjects: |
Teenage pregnancy, Bipolar disorder, Mental depression, Schizophrenia, Mental health screening, Cohort analysis, Disease risk factors, Psychiatric diagnosis |
| Abstract: |
Aim: Adolescent pregnancy is a global public health concern associated with increased risks of physical health, mental well‐being, and social functioning; however, its potential to increase the long‐term risk of major psychiatric disorder (MPD) remains underexplored. Methods: Between 1996 and 2013, a cohort of 29,974 girls with adolescent pregnancy without MPD before and 1:4 matched controls based on age, family income, residence location, and individual psychiatric comorbidity were enrolled. A Cox regression model was used, adjusted for potential confounders, to estimate the risk of schizophrenia, bipolar disorder, and major depressive disorder (MDD). Results: After adjusting for confounding factors, adolescent pregnancy was associated with significantly increased risks of bipolar disorder (hazard ratio 1.44; 95% confidence interval 1.20–1.72) and MDD (1.88; 1.76–2.00), but not schizophrenia (0.94; 0.73–1.21), compared to the control group. These associations persisted after excluding the first 3 years of follow‐up, with elevated risks of bipolar disorder (1.27; 1.05–1.54) and MDD (1.61; 1.50–1.72) among adolescents with pregnancy compared to controls. Conclusions: These results underscore the importance of implementing long‐term mental health surveillance strategies for young mothers who experience adolescent pregnancy. [ABSTRACT FROM AUTHOR] |
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| Database: |
Psychology and Behavioral Sciences Collection |