Obstetric complications, the putative familial-sporadic distinction, and tardive dyskinesia in schizophrenia.

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Bibliographic Details
Title: Obstetric complications, the putative familial-sporadic distinction, and tardive dyskinesia in schizophrenia.
Authors: O'Callaghan, Eadbhard, Larkin, Conall, Kinsella, Anthony, Waddington, John L., O'Callaghan, E (AUTHOR), Larkin, C (AUTHOR), Kinsella, A (AUTHOR), Waddington, J L (AUTHOR)
Source: British Journal of Psychiatry. Oct90, Vol. 157, p578-584. 7p.
Subjects: Tardive dyskinesia, Schizophrenia treatment, Obstetrics, Side effects of psychiatric drugs, Genealogy, Mental illness, Drug therapy for schizophrenia, Brain damage complications, Antipsychotic agents, Brain damage, Comparative studies, Controlled release preparations, Labor complications (Obstetrics), Research methodology, Medical cooperation, Psychology, Research, Schizophrenia, Evaluation research
Abstract: Obstetric complications were more common in the histories of those schizophrenic outpatients without a family history of psychiatric disorder, and were associated with an earlier onset of their illness. Those patients with tardive dyskinesia were more likely to have a family history of psychiatric disorder, less likely to have experienced obstetric complications, and showed greater cognitive deficit. Obstetric complications should be considered in juxtaposition with genetic factors in evaluating the putative familial-sporadic distinction in schizophrenia. Additionally, familial/genetic factors appears to contribute to vulnerability to tardive dyskinesia. [ABSTRACT FROM AUTHOR]
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Database: Psychology and Behavioral Sciences Collection
Description
Abstract:Obstetric complications were more common in the histories of those schizophrenic outpatients without a family history of psychiatric disorder, and were associated with an earlier onset of their illness. Those patients with tardive dyskinesia were more likely to have a family history of psychiatric disorder, less likely to have experienced obstetric complications, and showed greater cognitive deficit. Obstetric complications should be considered in juxtaposition with genetic factors in evaluating the putative familial-sporadic distinction in schizophrenia. Additionally, familial/genetic factors appears to contribute to vulnerability to tardive dyskinesia. [ABSTRACT FROM AUTHOR]
ISSN:00071250
DOI:10.1192/bjp.157.4.578