Sleep disturbance and daytime sleepiness in patients with cirrhosis: a case control study.

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Bibliographic Details
Title:	Sleep disturbance and daytime sleepiness in patients with cirrhosis: a case control study.
Authors:	Mostacci, Barbara, Ferlisi, Monica, Antognini, Alessandro Baldi, Sama, Claudia, Morelli, Cristina, Mondini, Susanna, Cirignotta, Fabio
Source:	Neurological Sciences. Sep2008, Vol. 29 Issue 4, p237-240. 4p. 1 Chart.
Subjects:	Sleep disorders, Cirrhosis of the liver, Drowsiness, Patients, Sleep
Abstract:	Sleep disturbance and excessive daytime sleepiness have been reported in patients with hepatic cirrhosis. The objective of this study was to evaluate daytime somnolence and sleep complaints in a group of 178 patients with cirrhosis compared to a control group. Sleep features and excessive daytime sleepiness were evaluated by the Basic Nordic Sleep Questionnaire (BNSQ) and the Epworth Sleepiness Scale (ESS). We collected clinical and laboratory data, neurological assessment and EEG recordings in cirrhotic patients. Patients with cirrhosis complained of more daytime sleepiness ( p<0.005), sleeping badly at least three times a week ( p<0.005), difficulties falling asleep ( p<0.01) and frequent nocturnal awakening ( p<0.005) than controls. We found a poor correlation between sleep disorders and clinical or laboratory parameters. Our results confirm previous literature reports suggesting a high prevalence of sleep disturbance in patients with cirrhosis. Insomnia and daytime sleepiness are the main complaints. Sleep disorders are probably a multifactorial phenomenon. [ABSTRACT FROM AUTHOR]
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Database:	Psychology and Behavioral Sciences Collection

Description
Abstract:	Sleep disturbance and excessive daytime sleepiness have been reported in patients with hepatic cirrhosis. The objective of this study was to evaluate daytime somnolence and sleep complaints in a group of 178 patients with cirrhosis compared to a control group. Sleep features and excessive daytime sleepiness were evaluated by the Basic Nordic Sleep Questionnaire (BNSQ) and the Epworth Sleepiness Scale (ESS). We collected clinical and laboratory data, neurological assessment and EEG recordings in cirrhotic patients. Patients with cirrhosis complained of more daytime sleepiness ( p<0.005), sleeping badly at least three times a week ( p<0.005), difficulties falling asleep ( p<0.01) and frequent nocturnal awakening ( p<0.005) than controls. We found a poor correlation between sleep disorders and clinical or laboratory parameters. Our results confirm previous literature reports suggesting a high prevalence of sleep disturbance in patients with cirrhosis. Insomnia and daytime sleepiness are the main complaints. Sleep disorders are probably a multifactorial phenomenon. [ABSTRACT FROM AUTHOR]
ISSN:	15901874
DOI:	10.1007/s10072-008-0973-7