Bibliographic Details
| Title: |
Questioning the role of rebound firing in the cerebellum. |
| Authors: |
Alviña, Karina, Walter, Joy T., Kohn, Adam, Ellis-Davies, Graham, Khodakhah, Kamran |
| Source: |
Nature Neuroscience. Nov2008, Vol. 11 Issue 11, p1256-1258. 3p. 1 Diagram, 2 Graphs. |
| Subjects: |
Cerebellar nuclei, Nervous system, Animal models in research, Transgenic mice, Neurosciences |
| Abstract: |
A key component of recent theories on cerebellar function is rebound firing in neurons of the deep cerebellar nuclei (DCN). Despite the robustness of this phenomenon in vitro, in vivo studies have provided little evidence for its prevalence. We found that intact mouse or rat DCN neurons rarely showed rebound firing under physiological conditions in vitro or in vivo. These observations necessitate a critical re-evaluation of recent cerebellar models. [ABSTRACT FROM AUTHOR] |
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| Database: |
Psychology and Behavioral Sciences Collection |
