Arkadia enhances nodal-related signalling to induce mesendoderm.

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Bibliographic Details
Title:	Arkadia enhances nodal-related signalling to induce mesendoderm.
Authors:	Niederlander, Christiane, Walsh, James J., Episkopou, Vasso, Jones, C. Michael
Source:	Nature. 4/12/2001, Vol. 410 Issue 6830, p830. 5p. 52 Color Photographs, 7 Diagrams.
Subjects:	Nucleoproteins, Transforming growth factors-beta, Immunomodulators, Biology
Abstract:	Presents a study to investigate the function of Arkadia and its role in establishing Spemann's organizer. How the nuclear protein Arkadia specifically potentiates the mesendoderm-inducing activity of a subset of transforming growth factor (TGF)-beta family members; Identification of Arkadia as an essential modulator of the nodal signalling cascade that leads to induction of Spemann's organizer.
Database:	Psychology and Behavioral Sciences Collection

Description
Abstract:	Presents a study to investigate the function of Arkadia and its role in establishing Spemann's organizer. How the nuclear protein Arkadia specifically potentiates the mesendoderm-inducing activity of a subset of transforming growth factor (TGF)-beta family members; Identification of Arkadia as an essential modulator of the nodal signalling cascade that leads to induction of Spemann's organizer.
ISSN:	00280836