Bibliographic Details
| Title: |
Cancer biology: Cancer's metabolic roots. |
| Source: |
Nature. 7/30/2009, Vol. 460 Issue 7255, p554-554. 1p. |
| Subjects: |
Tumor genetics, Genetic mutation, Rutter, Jared, Succinate dehydrogenase, Carcinogenesis, Neuroendocrine tumors |
| Abstract: |
The article cites a study which found a link between a mutation in a protein and a development of a type of tumour. A team led by Jared Rutter determined the function of SDH5, a structural protein of the enzyme succinate dehydrogenase (SDH). It is noted that the neuroendocrine tumour called paraganglioma is attributed to human mutations that inhibit SDH activity, thus signifying a metabolic cause of the tumour. |
| Database: |
Psychology and Behavioral Sciences Collection |
