Bibliographic Details
| Title: |
A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction. |
| Authors: |
Clement, Karine, Vaisse, Christian, Lahlou, Najiba, Cabrol, Sylvie, Pelloux, Veronique, Cassuto, Dominique, Gourmelen, Micheline, Dina, Christian, Chambaz, Jean, Lacorte, Jean-Marc, Basdevant, Arnaud, Bougnères, Pierre, Lebouc, Yves, Froguel, Philippe, Guy-Grand, Bernard |
| Source: |
Nature. 3/26/1998, Vol. 392 Issue 6674, p398. 4p. 5 Black and White Photographs, 2 Diagrams, 2 Charts, 3 Graphs. |
| Subjects: |
Sex hormone receptors, Obesity genetics, Pituitary hormone releasing factors |
| Abstract: |
Presents research which described a homozygous mutation in the human leptin receptor gene. Leptin's regulation of adipose-tissue mass; Leptin receptors; Homozygous mutations in genes encoding leptin in mice; Effects in humans of leptin deficiency due to mutation; Traits of such patients; Leptin's role in human endocrine functions. |
| Database: |
Psychology and Behavioral Sciences Collection |
