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A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction.

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Title: A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction.
Authors: Clement, Karine, Vaisse, Christian, Lahlou, Najiba, Cabrol, Sylvie, Pelloux, Veronique, Cassuto, Dominique, Gourmelen, Micheline, Dina, Christian, Chambaz, Jean, Lacorte, Jean-Marc, Basdevant, Arnaud, Bougnères, Pierre, Lebouc, Yves, Froguel, Philippe, Guy-Grand, Bernard
Source: Nature. 3/26/1998, Vol. 392 Issue 6674, p398. 4p. 5 Black and White Photographs, 2 Diagrams, 2 Charts, 3 Graphs.
Subjects: Sex hormone receptors, Obesity genetics, Pituitary hormone releasing factors
Abstract: Presents research which described a homozygous mutation in the human leptin receptor gene. Leptin's regulation of adipose-tissue mass; Leptin receptors; Homozygous mutations in genes encoding leptin in mice; Effects in humans of leptin deficiency due to mutation; Traits of such patients; Leptin's role in human endocrine functions.
Database: Psychology and Behavioral Sciences Collection
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DbLabel: Psychology and Behavioral Sciences Collection
An: 435488
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
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  Data: A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction.
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  Data: <searchLink fieldCode="AR" term="%22Clement%2C+Karine%22">Clement, Karine</searchLink><br /><searchLink fieldCode="AR" term="%22Vaisse%2C+Christian%22">Vaisse, Christian</searchLink><br /><searchLink fieldCode="AR" term="%22Lahlou%2C+Najiba%22">Lahlou, Najiba</searchLink><br /><searchLink fieldCode="AR" term="%22Cabrol%2C+Sylvie%22">Cabrol, Sylvie</searchLink><br /><searchLink fieldCode="AR" term="%22Pelloux%2C+Veronique%22">Pelloux, Veronique</searchLink><br /><searchLink fieldCode="AR" term="%22Cassuto%2C+Dominique%22">Cassuto, Dominique</searchLink><br /><searchLink fieldCode="AR" term="%22Gourmelen%2C+Micheline%22">Gourmelen, Micheline</searchLink><br /><searchLink fieldCode="AR" term="%22Dina%2C+Christian%22">Dina, Christian</searchLink><br /><searchLink fieldCode="AR" term="%22Chambaz%2C+Jean%22">Chambaz, Jean</searchLink><br /><searchLink fieldCode="AR" term="%22Lacorte%2C+Jean-Marc%22">Lacorte, Jean-Marc</searchLink><br /><searchLink fieldCode="AR" term="%22Basdevant%2C+Arnaud%22">Basdevant, Arnaud</searchLink><br /><searchLink fieldCode="AR" term="%22Bougnères%2C+Pierre%22">Bougnères, Pierre</searchLink><br /><searchLink fieldCode="AR" term="%22Lebouc%2C+Yves%22">Lebouc, Yves</searchLink><br /><searchLink fieldCode="AR" term="%22Froguel%2C+Philippe%22">Froguel, Philippe</searchLink><br /><searchLink fieldCode="AR" term="%22Guy-Grand%2C+Bernard%22">Guy-Grand, Bernard</searchLink>
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  Data: <searchLink fieldCode="JN" term="%22Nature%22">Nature</searchLink>. 3/26/1998, Vol. 392 Issue 6674, p398. 4p. 5 Black and White Photographs, 2 Diagrams, 2 Charts, 3 Graphs.
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  Data: <searchLink fieldCode="DE" term="%22Sex+hormone+receptors%22">Sex hormone receptors</searchLink><br /><searchLink fieldCode="DE" term="%22Obesity+genetics%22">Obesity genetics</searchLink><br /><searchLink fieldCode="DE" term="%22Pituitary+hormone+releasing+factors%22">Pituitary hormone releasing factors</searchLink>
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  Data: Presents research which described a homozygous mutation in the human leptin receptor gene. Leptin's regulation of adipose-tissue mass; Leptin receptors; Homozygous mutations in genes encoding leptin in mice; Effects in humans of leptin deficiency due to mutation; Traits of such patients; Leptin's role in human endocrine functions.
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=435488
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      – Code: eng
        Text: English
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        PageCount: 4
        StartPage: 398
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      – SubjectFull: Sex hormone receptors
        Type: general
      – SubjectFull: Obesity genetics
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      – SubjectFull: Pituitary hormone releasing factors
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      – TitleFull: A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction.
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              Text: 3/26/1998
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              Y: 1998
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