Sleep Patterns in Patients With Huntington's Disease and Their Unaffected First-Degree Relatives: A Brief Report.
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| Title: | Sleep Patterns in Patients With Huntington's Disease and Their Unaffected First-Degree Relatives: A Brief Report. |
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| Authors: | Cuturic, Miroslav (AUTHOR), Abramson, RuthK. (AUTHOR), Vallini, Daniel (AUTHOR), Frank, ElaineM. (AUTHOR), Shamsnia, Morteza (AUTHOR) |
| Source: | Behavioral Sleep Medicine. Oct-Dec2009, Vol. 7 Issue 4, p245-254. 10p. 1 Diagram, 4 Charts. |
| Subjects: | Somnology, Sleep disorder diagnosis, Huntington disease, Chorea, Genetic markers, Trait intercorrelations, Polysomnography, Patient psychology, Psychology, Patients, Genetics, Therapeutics |
| Abstract: | Polysomnographic sleep patterns in Huntington's disease (HD) have been studied sporadically in small groups of patients, providing variable results. In this study, by comparing the polysomnographic sleep patterns of HD patients and their unaffected relatives, identifying sleep traits more specifically related to the HD gene was attempted. The results corroborated previously reported findings of prolonged sleep latency and the virtual absence of nocturnal respiratory disturbances in early HD. Sleep latency in the HD patients positively correlated with the results of a screening test for frontal lobe dysfunction. Larger, more standardized studies will be needed to correlate genetic markers and sleep patterns in HD. [ABSTRACT FROM AUTHOR] |
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| Database: | Psychology and Behavioral Sciences Collection |
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| Abstract: | Polysomnographic sleep patterns in Huntington's disease (HD) have been studied sporadically in small groups of patients, providing variable results. In this study, by comparing the polysomnographic sleep patterns of HD patients and their unaffected relatives, identifying sleep traits more specifically related to the HD gene was attempted. The results corroborated previously reported findings of prolonged sleep latency and the virtual absence of nocturnal respiratory disturbances in early HD. Sleep latency in the HD patients positively correlated with the results of a screening test for frontal lobe dysfunction. Larger, more standardized studies will be needed to correlate genetic markers and sleep patterns in HD. [ABSTRACT FROM AUTHOR] |
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| ISSN: | 15402002 |
| DOI: | 10.1080/15402000903190215 |
