Prevalence and determinants of carotid artery stenosis.

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Bibliographic Details
Title:	Prevalence and determinants of carotid artery stenosis.
Authors:	Mathiesen*†, Ellisiv B., Bønaa, Kaare H., Joakimsen†, Oddmund
Source:	Acta Neurologica Scandinavica. May2001, Vol. 103 Issue 5, p327. 7p.
Subjects:	Carotid artery diseases, Arterial stenosis
Abstract:	Purpose: To assess prevalence, distribution, ultrasound characteristics and determinants of carotid artery stenosis in a large, population-based study of both women and men. Methods: A total of 6727 persons aged 25-84 years were screened for extracranial stenosis with Duplex ultrasound of the right carotid artery. Risk factors were compared in 225 persons with stenosis and 5514 persons without. Results: Carotid stenosis was not observed in subjects below 50 years of age. The prevalence of carotid stenosis was highest in men, where 3.8% (95% CI 3.2-4.6%) had carotid stenosis, compared to 2.7% (95% CI 2.2-3.3%) in women (p=0.001). The prevalence gradually increased by age in both genders. Total cholesterol, HDL cholesterol, fibrinogen, systolic blood pressure and current smoking were independently associated with carotid artery stenosis in both women and men. Carotid stenosis was also associated with coronary heart disease and peripheral artery disease. Conclusion: The prevalence of carotid stenosis in the general population, as measured by ultrasound, is low. Age, male gender, smoking, total cholesterol, HDL cholesterol (inverse), fibrinogen, and systolic blood pressure are all independent predictors of carotid artery stenosis. [ABSTRACT FROM AUTHOR]
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Database:	Psychology and Behavioral Sciences Collection

Description
Abstract:	Purpose: To assess prevalence, distribution, ultrasound characteristics and determinants of carotid artery stenosis in a large, population-based study of both women and men. Methods: A total of 6727 persons aged 25-84 years were screened for extracranial stenosis with Duplex ultrasound of the right carotid artery. Risk factors were compared in 225 persons with stenosis and 5514 persons without. Results: Carotid stenosis was not observed in subjects below 50 years of age. The prevalence of carotid stenosis was highest in men, where 3.8% (95% CI 3.2-4.6%) had carotid stenosis, compared to 2.7% (95% CI 2.2-3.3%) in women (p=0.001). The prevalence gradually increased by age in both genders. Total cholesterol, HDL cholesterol, fibrinogen, systolic blood pressure and current smoking were independently associated with carotid artery stenosis in both women and men. Carotid stenosis was also associated with coronary heart disease and peripheral artery disease. Conclusion: The prevalence of carotid stenosis in the general population, as measured by ultrasound, is low. Age, male gender, smoking, total cholesterol, HDL cholesterol (inverse), fibrinogen, and systolic blood pressure are all independent predictors of carotid artery stenosis. [ABSTRACT FROM AUTHOR]
ISSN:	00016314