Survival effect of para-aortic lymphadenectomy in endometrial cancer (SEPAL study): a retrospective cohort analysis.

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Bibliographic Details
Title: Survival effect of para-aortic lymphadenectomy in endometrial cancer (SEPAL study): a retrospective cohort analysis.
Authors: Todo, Yukiharu, Kato, Hidenori, Kaneuchi, Masanori, Watari, Hidemichi, Takeda, Mahito, Sakuragi, Noriaki
Source: Lancet. 4/3/2010, Vol. 375 Issue 9721, p1165-1172. 8p. 1 Diagram, 8 Charts, 1 Graph.
Subjects: Lymph node surgery, Endometrial surgery, Endometrial cancer, Cancer relapse, Metastasis, Cohort analysis, Prevention
Geographic Terms: Japan
Abstract: The article discusses a study which investigated the effect of para-aortic lymphadenectomy on patients at intermediate and high risk of recurrence of endometrial cancer. The retrospective cohort analysis involved 671 patients with endometrial carcinoma, who received systematic pelvic lymphadenectomy or combined pelvic and para-aortic lymphadenectomy in Japan. The researchers have found that para-aortic lymphadenectomy increased survival rates in patients at intermediate or high risk or recurrence.
Database: Psychology and Behavioral Sciences Collection
Description
Abstract:The article discusses a study which investigated the effect of para-aortic lymphadenectomy on patients at intermediate and high risk of recurrence of endometrial cancer. The retrospective cohort analysis involved 671 patients with endometrial carcinoma, who received systematic pelvic lymphadenectomy or combined pelvic and para-aortic lymphadenectomy in Japan. The researchers have found that para-aortic lymphadenectomy increased survival rates in patients at intermediate or high risk or recurrence.
ISSN:01406736
DOI:10.1016/S0140-6736(09)62002-X