Longitudinal study of the socioeconomic burden of Parkinson’s disease in Germany.

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Bibliographic Details
Title:	Longitudinal study of the socioeconomic burden of Parkinson’s disease in Germany.
Authors:	Winter, Y., Balzer-Geldsetzer, M., Spottke, A., Reese, J. P., Baum, E., Klotsche, J., Rieke, J., Simonow, A., Eggert, K., Oertel, W. H., Dodel, Richard
Source:	European Journal of Neurology. Sep2010, Vol. 17 Issue 9, p1156-1163. 8p. 5 Charts, 1 Graph.
Subjects:	Medical economics, Parkinson's disease, Regression analysis, Medical care
Geographic Terms:	Germany
Abstract:	Objective: To determine the health economic burden on patients with Parkinson’s disease (PD) in Germany over a 12-month observation period and provide a comprehensive analysis of cost-driving factors. Methods and patients: Patients with PD ( n = 145) were recruited from two clinical departments, two office-based neurologists and 12 GPs. Clinical evaluations were performed at baseline, 3, 6 and 12 months. Disease severity was measured using the Unified Parkinson’s Disease Rating Scale (UPDRS). Cost data were assessed based on a patient diary and via personal structured interviews at the respective time-points. Costs were calculated from the societal perspective (2009 €). Cost-driving factors were identified by multivariate regression analysis. Results: Mean annual costs totalled €20 095 per patient. Amongst direct costs, the highest expenditures (€13 158) were for drugs (€3526) and inpatient care including nursing homes (€3789). Indirect costs accounted for 34.5% (€6937) of total costs. Costs of home care provided by family accounted for 20% of direct costs. Cost-driving factors were identified for total costs (UPDRS, fluctuations, dyskinesia and younger age), direct costs (UPDRS, fluctuations), patient expenditures (UPDRS, depression) and drug costs (younger age). Conclusion: Parkinson’s disease has a chronic course with growing disability and considerable socioeconomic burden. Disease progression leads to an increasing number of patients who require costly institutionalized care. Home care is a major factor influencing patients’ families. Healthcare programmes aimed at reducing the burden of PD on society and individuals should consider cost-driving factors of PD. [ABSTRACT FROM AUTHOR]
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Database:	Psychology and Behavioral Sciences Collection

Description
Abstract:	Objective: To determine the health economic burden on patients with Parkinson’s disease (PD) in Germany over a 12-month observation period and provide a comprehensive analysis of cost-driving factors. Methods and patients: Patients with PD ( n = 145) were recruited from two clinical departments, two office-based neurologists and 12 GPs. Clinical evaluations were performed at baseline, 3, 6 and 12 months. Disease severity was measured using the Unified Parkinson’s Disease Rating Scale (UPDRS). Cost data were assessed based on a patient diary and via personal structured interviews at the respective time-points. Costs were calculated from the societal perspective (2009 €). Cost-driving factors were identified by multivariate regression analysis. Results: Mean annual costs totalled €20 095 per patient. Amongst direct costs, the highest expenditures (€13 158) were for drugs (€3526) and inpatient care including nursing homes (€3789). Indirect costs accounted for 34.5% (€6937) of total costs. Costs of home care provided by family accounted for 20% of direct costs. Cost-driving factors were identified for total costs (UPDRS, fluctuations, dyskinesia and younger age), direct costs (UPDRS, fluctuations), patient expenditures (UPDRS, depression) and drug costs (younger age). Conclusion: Parkinson’s disease has a chronic course with growing disability and considerable socioeconomic burden. Disease progression leads to an increasing number of patients who require costly institutionalized care. Home care is a major factor influencing patients’ families. Healthcare programmes aimed at reducing the burden of PD on society and individuals should consider cost-driving factors of PD. [ABSTRACT FROM AUTHOR]
ISSN:	13515101
DOI:	10.1111/j.1468-1331.2010.02984.x