Bibliographic Details
| Title: |
Epidemiology of progressive supranuclear palsy. |
| Authors: |
Vanacore, N., Bonifati, V., Colosimo, C., Fabbrini, G., De Michele, G., Marconi, R., Nicholl, D., Locuratolo, N., Romano, S., Talarico, G., Stocchi, F., Bonuccelli, U., Lamberti, P., Vieregge, P., Meco, G. |
| Source: |
Neurological Sciences. Feb2001, Vol. 22 Issue 1, p101. 3p. |
| Subjects: |
Progressive supranuclear palsy, Dementia, Parkinson's disease |
| Abstract: |
Progressive supranuclear palsy (PSP) is a rare form of parkinsonism. The incidence rates are about 0.3–1.1 cases per 100 000 persons. The only two-case-control studies performed up to now show conflictual results as regards education and residence in rural areas. Recently, a cluster of PSP and atypical parkinsonism has been observed in French Antilles. The hypothesis is that a consumption of both tropical fruit and herbal tea may be associated with PSP onset. Some PSP families with a probably autosomal dominant transmission have been described. A high frequency of a tau haplotype (H[sub 1] /H[sub 1] ) associated with PSP is reported by some authors. The significance of this association is still not clear. We have performed a case-control study on 58 PSP cases, 116 hospital controls and 58 population controls. [ABSTRACT FROM AUTHOR] |
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| Database: |
Psychology and Behavioral Sciences Collection |