Evaluating depressive symptoms and their impact on outcome in schizophrenia applying the Calgary Depression Scale.
Saved in:
| Title: | Evaluating depressive symptoms and their impact on outcome in schizophrenia applying the Calgary Depression Scale. |
|---|---|
| Authors: | Schennach‐Wolff, R. (AUTHOR), Obermeier, M. (AUTHOR), Seemüller, F. (AUTHOR), Jäger, M. (AUTHOR), Messer, T. (AUTHOR), Laux, G. (AUTHOR), Pfeiffer, H. (AUTHOR), Naber, D. (AUTHOR), Schmidt, L. G. (AUTHOR), Gaebel, W. (AUTHOR), Klosterkötter, J. (AUTHOR), Heuser, I. (AUTHOR), Maier, W. (AUTHOR), Lemke, M. R. (AUTHOR), Rüther, E. (AUTHOR), Klingberg, S. (AUTHOR), Gastpar, M. (AUTHOR), Möller, H.‐J. (AUTHOR), Riedel, M. (AUTHOR) |
| Source: | Acta Psychiatrica Scandinavica. Mar2011, Vol. 123 Issue 3, p228-238. 11p. 9 Charts, 4 Graphs. |
| Subjects: | Mental depression, Schizophrenia, Symptoms, Pathological psychology, Mental illness treatment |
| Abstract: | Schennach-Wolff R, Obermeier M, Seemüller F, Jäger M, Messer T, Laux G, Pfeiffer H, Naber D, Schmidt LG, Gaebel W, Klosterkötter J, Heuser I, Maier W, Lemke MR, Rüther E, Klingberg S, Gastpar M, Möller H-J, Riedel M. Evaluating depressive symptoms and their impact on outcome in schizophrenia applying the Calgary Depression Scale. To examine depressive symptoms, their course during treatment, and influence on outcome. Weekly Calgary Depression Scale for Schizophrenia ratings were performed in 249 inpatients with schizophrenia. Early response was defined as a 20% reduction in the total score of the Positive and Negative Syndrome Scale for Schizophrenia from admission to week 2, response as a 50% reduction in the total score of the Positive and Negative Syndrome Scale for Schizophrenia (PANSS) from admission to discharge and remission according to the consensus criteria. Thirty six per cent of the patients were depressed at admission, with 23% of them still being depressed at discharge. Depressed patients scored significantly higher on the PANSS negative and general psychopathology subscore, featured more impairments in subjective well-being ( P < 0.0001) and functioning ( P < 0.0001). They suffered from more suicidality ( P = 0.0021), and had greater insight into their illness ( P = 0.0105). No significant differences were found regarding early response, response, and remission. Patients with depressive symptoms should be monitored closely, given the burden of negative symptoms, their impairments in well-being and functioning and the threat of suicidality. [ABSTRACT FROM AUTHOR] |
| Copyright of Acta Psychiatrica Scandinavica is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
|
Full text is not displayed to guests.
Login for full access.
|
|
| Abstract: | Schennach-Wolff R, Obermeier M, Seemüller F, Jäger M, Messer T, Laux G, Pfeiffer H, Naber D, Schmidt LG, Gaebel W, Klosterkötter J, Heuser I, Maier W, Lemke MR, Rüther E, Klingberg S, Gastpar M, Möller H-J, Riedel M. Evaluating depressive symptoms and their impact on outcome in schizophrenia applying the Calgary Depression Scale. To examine depressive symptoms, their course during treatment, and influence on outcome. Weekly Calgary Depression Scale for Schizophrenia ratings were performed in 249 inpatients with schizophrenia. Early response was defined as a 20% reduction in the total score of the Positive and Negative Syndrome Scale for Schizophrenia from admission to week 2, response as a 50% reduction in the total score of the Positive and Negative Syndrome Scale for Schizophrenia (PANSS) from admission to discharge and remission according to the consensus criteria. Thirty six per cent of the patients were depressed at admission, with 23% of them still being depressed at discharge. Depressed patients scored significantly higher on the PANSS negative and general psychopathology subscore, featured more impairments in subjective well-being ( P < 0.0001) and functioning ( P < 0.0001). They suffered from more suicidality ( P = 0.0021), and had greater insight into their illness ( P = 0.0105). No significant differences were found regarding early response, response, and remission. Patients with depressive symptoms should be monitored closely, given the burden of negative symptoms, their impairments in well-being and functioning and the threat of suicidality. [ABSTRACT FROM AUTHOR] |
|---|---|
| ISSN: | 0001690X |
| DOI: | 10.1111/j.1600-0447.2010.01608.x |
