Bibliographic Details
| Title: |
Synaptic modulators Nrxn1 and Nrxn3 are disregulated in a Disc1 mouse model of schizophrenia. |
| Authors: |
Brown, S. M., Clapcote, S. J., Millar, J. K., Torrance, H. S., Anderson, S. M., Walker, R., Rampino, A., Roder, J. C., Thomson, P. A., Porteous, D. J., Evans, K. L. |
| Source: |
Molecular Psychiatry. Jun2011, Vol. 16 Issue 6, p585-587. 3p. 1 Graph. |
| Subjects: |
Letters to the editor, Synapses, Laboratory mice, Physiology |
| Abstract: |
A letter to the editor is presented regarding the characterization of synaptic modulators Nrxn1 and Nrxn3 in schizophrenia as demonstrated by a study using a mouse line with ENU-induced Disc1, a principal candidate gene for schizophrenia, L100P mutation, which resulted in disregulation of synaptic modulators expression at key points during a mouse's development as well as in adult mice. |
| Database: |
Psychology and Behavioral Sciences Collection |
