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Synaptic modulators Nrxn1 and Nrxn3 are disregulated in a Disc1 mouse model of schizophrenia.

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Title: Synaptic modulators Nrxn1 and Nrxn3 are disregulated in a Disc1 mouse model of schizophrenia.
Authors: Brown, S. M., Clapcote, S. J., Millar, J. K., Torrance, H. S., Anderson, S. M., Walker, R., Rampino, A., Roder, J. C., Thomson, P. A., Porteous, D. J., Evans, K. L.
Source: Molecular Psychiatry. Jun2011, Vol. 16 Issue 6, p585-587. 3p. 1 Graph.
Subjects: Letters to the editor, Synapses, Laboratory mice, Physiology
Abstract: A letter to the editor is presented regarding the characterization of synaptic modulators Nrxn1 and Nrxn3 in schizophrenia as demonstrated by a study using a mouse line with ENU-induced Disc1, a principal candidate gene for schizophrenia, L100P mutation, which resulted in disregulation of synaptic modulators expression at key points during a mouse's development as well as in adult mice.
Database: Psychology and Behavioral Sciences Collection
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PubType: Academic Journal
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  Data: Synaptic modulators Nrxn1 and Nrxn3 are disregulated in a Disc1 mouse model of schizophrenia.
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  Data: <searchLink fieldCode="JN" term="%22Molecular+Psychiatry%22">Molecular Psychiatry</searchLink>. Jun2011, Vol. 16 Issue 6, p585-587. 3p. 1 Graph.
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  Data: A letter to the editor is presented regarding the characterization of synaptic modulators Nrxn1 and Nrxn3 in schizophrenia as demonstrated by a study using a mouse line with ENU-induced Disc1, a principal candidate gene for schizophrenia, L100P mutation, which resulted in disregulation of synaptic modulators expression at key points during a mouse's development as well as in adult mice.
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              Text: Jun2011
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