Bibliographic Details
| Title: |
Neuronal activity drives matching of pre- and postsynaptic function during synapse maturation. |
| Authors: |
Kay, Louise, Humphreys, Lawrence, Eickholt, Britta J, Burrone, Juan |
| Source: |
Nature Neuroscience. Jun2011, Vol. 14 Issue 6, p688-690. 3p. 2 Graphs. |
| Subjects: |
Neurons, Axons, Tetrodotoxin, Glutamic acid, Green fluorescent protein, Synaptic vesicles |
| Abstract: |
The structure and function of presynaptic and postsynaptic compartments varies markedly in neurons, but little is known about how they are functionally arranged with respect to each other. In rat hippocampal neurons, we found that, although they are structurally correlated from the early moments of formation, synapses only gradually become functionally matched and that this process is dependent on ongoing electrical activity. [ABSTRACT FROM AUTHOR] |
|
Copyright of Nature Neuroscience is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| Database: |
Psychology and Behavioral Sciences Collection |
