View in EDS PDF Full Text

Neuronal activity drives matching of pre- and postsynaptic function during synapse maturation.

Saved in:
Bibliographic Details
Title: Neuronal activity drives matching of pre- and postsynaptic function during synapse maturation.
Authors: Kay, Louise, Humphreys, Lawrence, Eickholt, Britta J, Burrone, Juan
Source: Nature Neuroscience. Jun2011, Vol. 14 Issue 6, p688-690. 3p. 2 Graphs.
Subjects: Neurons, Axons, Tetrodotoxin, Glutamic acid, Green fluorescent protein, Synaptic vesicles
Abstract: The structure and function of presynaptic and postsynaptic compartments varies markedly in neurons, but little is known about how they are functionally arranged with respect to each other. In rat hippocampal neurons, we found that, although they are structurally correlated from the early moments of formation, synapses only gradually become functionally matched and that this process is dependent on ongoing electrical activity. [ABSTRACT FROM AUTHOR]
Copyright of Nature Neuroscience is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
FullText Links:
  – Type: pdflink
Text:
  Availability: 0
Header DbId: pbh
DbLabel: Psychology and Behavioral Sciences Collection
An: 60832248
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Neuronal activity drives matching of pre- and postsynaptic function during synapse maturation.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Kay%2C+Louise%22">Kay, Louise</searchLink><br /><searchLink fieldCode="AR" term="%22Humphreys%2C+Lawrence%22">Humphreys, Lawrence</searchLink><br /><searchLink fieldCode="AR" term="%22Eickholt%2C+Britta+J%22">Eickholt, Britta J</searchLink><br /><searchLink fieldCode="AR" term="%22Burrone%2C+Juan%22">Burrone, Juan</searchLink>
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22Nature+Neuroscience%22">Nature Neuroscience</searchLink>. Jun2011, Vol. 14 Issue 6, p688-690. 3p. 2 Graphs.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22Neurons%22">Neurons</searchLink><br /><searchLink fieldCode="DE" term="%22Axons%22">Axons</searchLink><br /><searchLink fieldCode="DE" term="%22Tetrodotoxin%22">Tetrodotoxin</searchLink><br /><searchLink fieldCode="DE" term="%22Glutamic+acid%22">Glutamic acid</searchLink><br /><searchLink fieldCode="DE" term="%22Green+fluorescent+protein%22">Green fluorescent protein</searchLink><br /><searchLink fieldCode="DE" term="%22Synaptic+vesicles%22">Synaptic vesicles</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: The structure and function of presynaptic and postsynaptic compartments varies markedly in neurons, but little is known about how they are functionally arranged with respect to each other. In rat hippocampal neurons, we found that, although they are structurally correlated from the early moments of formation, synapses only gradually become functionally matched and that this process is dependent on ongoing electrical activity. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Nature Neuroscience is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=60832248
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1038/nn.2826
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 3
        StartPage: 688
    Subjects:
      – SubjectFull: Neurons
        Type: general
      – SubjectFull: Axons
        Type: general
      – SubjectFull: Tetrodotoxin
        Type: general
      – SubjectFull: Glutamic acid
        Type: general
      – SubjectFull: Green fluorescent protein
        Type: general
      – SubjectFull: Synaptic vesicles
        Type: general
    Titles:
      – TitleFull: Neuronal activity drives matching of pre- and postsynaptic function during synapse maturation.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Kay, Louise
      – PersonEntity:
          Name:
            NameFull: Humphreys, Lawrence
      – PersonEntity:
          Name:
            NameFull: Eickholt, Britta J
      – PersonEntity:
          Name:
            NameFull: Burrone, Juan
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 06
              Text: Jun2011
              Type: published
              Y: 2011
          Identifiers:
            – Type: issn-print
              Value: 10976256
          Numbering:
            – Type: volume
              Value: 14
            – Type: issue
              Value: 6
          Titles:
            – TitleFull: Nature Neuroscience
              Type: main
ResultId 1