Bibliographic Details
| Title: |
The contribution of bone to whole-organism physiology. |
| Authors: |
Karsenty, Gérard, Ferron, Mathieu |
| Source: |
Nature. 1/19/2012, Vol. 481 Issue 7381, p314-320. 7p. 4 Diagrams. |
| Subjects: |
Physiological research, Gene expression, Laboratory mice, Skeleton, Energy metabolism regulation, Degeneration (Pathology), Anatomy |
| Abstract: |
The mouse genetic revolution has shown repeatedly that most organs have more functions than expected. This has led to the realization that, in addition to a molecular and cellular approach, there is a need for a whole-organism study of physiology. The skeleton is an example of how a whole-organism approach to physiology can broaden the functions of a given organ, reveal connections of this organ with others such as the brain, pancreas and gut, and shed new light on the pathogenesis of degenerative diseases affecting multiple organs. [ABSTRACT FROM AUTHOR] |
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| Database: |
Psychology and Behavioral Sciences Collection |
