Bibliographic Details
| Title: |
Emergence of artemisinin-resistant malaria on the western border of Thailand: a longitudinal study. |
| Authors: |
Aung Pyae Phyo, Nkhoma, Standwell, Stepniewska, Kasia, Ashley, Elizabeth A., Nair, Shalini, McGready, Rose, Moo, Carit ler, Al-Saai, Salma, Dondorp, Arjen M., Lwin, Khin Maung, Singhasivanon, Pratap, Day, Nicholas P. J., White, Nicholas J., Anderson, Tim J. C., Nosten, François |
| Source: |
Lancet. 5/26/2012, Vol. 379 Issue 9830, p1960-1966. 7p. |
| Subjects: |
Medical research, Artemisinin, Parasites, Plasmodium falciparum |
| Geographic Terms: |
Myanmar, Thailand |
| Abstract: |
The article presents a study that establishes whether artemisinin resistance has spread on the Thailand-Burma border. It shows that parasite clearance half-lives lengthened from a geometric mean of 6.2 hours in 2001 to 3.7 hours in 2010. It indicates that the proportion of slow-clearing infections has increased from 0.6% in 2011 to 20% in 2010. It reveals that genetically determined artemisinin resistance in Plasmodium falciparum emerged along the border at least eight years ago. |
| Database: |
Psychology and Behavioral Sciences Collection |
