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Computed tomographic colonography versus colonoscopy for investigation of patients with symptoms suggestive of colorectal cancer (SIGGAR): a multicentre randomised trial.

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Bibliographic Details
Title: Computed tomographic colonography versus colonoscopy for investigation of patients with symptoms suggestive of colorectal cancer (SIGGAR): a multicentre randomised trial.
Authors: Atkin, Wendy, Dadswell, Edward, Wooldrage, Kate, Kralj-Hans, Ines, von Wagner, Christian, Edwards, Rob, Guiqing Yao, Kay, Clive, Burling, David, Faiz, Omar, Teare, Julian, Lilford, Richard J., Morton, Dion, Wardle, Jane, Halligan, Steve
Source: Lancet. 4/6/2013, Vol. 381 Issue 9873, p1194-1202. 9p.
Subjects: Clinical trials, Virtual colonoscopy, Colon cancer diagnosis, Colonoscopy, Polyps, Diagnosis
Abstract: The article presents a multicentre randomised trial aimed at comparing the rates of additional colonic studies following computed tomographic colonography (CTC) as alternative to colonoscopy in patients with symptoms indicative of colorectal cancer. It suggests the need for guidelines to minimize the referral rate following CTC. Results demonstrate that CTC missed 1 of 29 colorectal cancers, while colonoscopy missed none, with no serious adverse reactions reported. INSET: Panel: Research in context.
Database: Psychology and Behavioral Sciences Collection
Description
Abstract:The article presents a multicentre randomised trial aimed at comparing the rates of additional colonic studies following computed tomographic colonography (CTC) as alternative to colonoscopy in patients with symptoms indicative of colorectal cancer. It suggests the need for guidelines to minimize the referral rate following CTC. Results demonstrate that CTC missed 1 of 29 colorectal cancers, while colonoscopy missed none, with no serious adverse reactions reported. INSET: Panel: Research in context.
ISSN:01406736
DOI:10.1016/S0140-6736(12)62186-2