Saliva cortisol and male depressive syndrome in a community study. The Sudurnesjamenn study.
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| Title: | Saliva cortisol and male depressive syndrome in a community study. The Sudurnesjamenn study. |
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| Authors: | Sigurdsson, Bjarni (AUTHOR), Palsson, Sigurdur Pall (AUTHOR), Johannsson, Magnus (AUTHOR), Olafsdottir, Maria (AUTHOR), Aevarsson, Olafur (AUTHOR) |
| Source: | Nordic Journal of Psychiatry. Jun2013, Vol. 67 Issue 3, p145-152. 8p. 2 Charts, 1 Graph. |
| Subjects: | Hydrocortisone, Mental depression, Hypothalamic-pituitary-adrenal axis, Mental health |
| Geographic Terms: | Montgomery (Ala.) |
| Abstract: | Background: The degree and direction of hypothalamic-pituitary-adrenal (HPA) dysfunction to male mental health is unclear. Aims: The aim of the study was to investigate the relationship between cortisol and male mental health. Methods: In this community study, 534 males were screened, using the Beck Depression Inventory (BDI), Gotland Male Depression Scale (GMDS) and a general health questionnaire. Those with signs of depression ( n = 65) and controls ( n = 69) were evaluated in a psychiatric examination according to the DSM-IV criteria for depressive disorder (DD). In a sub-sample ( n = 51) saliva cortisol was measured five times on a single day. Results: Evening cortisol was significantly higher in untreated individuals with DD. Significantly higher evening cortisol (at 22 h) correlated also with a history of physical disorder, a history of any mental disorder and MADRS score ≥ 20 (Montgomery-Åsberg Depression Rating Scale). High cortisol, measured as AUC (area under curve), correlated with a high MADRS score but not with any other health variable tested. Morning cortisol did not correlate with any health variable; however, cortisol awakening response (CAR) could not be investigated. The BDI and GMDS scores did not correlate with cortisol measurements. Conclusion: Evening saliva cortisol measurement seems most informative, as it correlates with male depressive syndrome in our study but replications with larger studies are needed. [ABSTRACT FROM AUTHOR] |
| Copyright of Nordic Journal of Psychiatry is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
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| Header | DbId: pbh DbLabel: Psychology and Behavioral Sciences Collection An: 87623306 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Saliva cortisol and male depressive syndrome in a community study. The Sudurnesjamenn study. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Sigurdsson%2C+Bjarni%22">Sigurdsson, Bjarni</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Palsson%2C+Sigurdur+Pall%22">Palsson, Sigurdur Pall</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Johannsson%2C+Magnus%22">Johannsson, Magnus</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Olafsdottir%2C+Maria%22">Olafsdottir, Maria</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Aevarsson%2C+Olafur%22">Aevarsson, Olafur</searchLink> (AUTHOR) – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Nordic+Journal+of+Psychiatry%22">Nordic Journal of Psychiatry</searchLink>. Jun2013, Vol. 67 Issue 3, p145-152. 8p. 2 Charts, 1 Graph. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Hydrocortisone%22">Hydrocortisone</searchLink><br /><searchLink fieldCode="DE" term="%22Mental+depression%22">Mental depression</searchLink><br /><searchLink fieldCode="DE" term="%22Hypothalamic-pituitary-adrenal+axis%22">Hypothalamic-pituitary-adrenal axis</searchLink><br /><searchLink fieldCode="DE" term="%22Mental+health%22">Mental health</searchLink> – Name: SubjectGeographic Label: Geographic Terms Group: Su Data: <searchLink fieldCode="DE" term="%22Montgomery+%28Ala%2E%29%22">Montgomery (Ala.)</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Background: The degree and direction of hypothalamic-pituitary-adrenal (HPA) dysfunction to male mental health is unclear. Aims: The aim of the study was to investigate the relationship between cortisol and male mental health. Methods: In this community study, 534 males were screened, using the Beck Depression Inventory (BDI), Gotland Male Depression Scale (GMDS) and a general health questionnaire. Those with signs of depression ( n = 65) and controls ( n = 69) were evaluated in a psychiatric examination according to the DSM-IV criteria for depressive disorder (DD). In a sub-sample ( n = 51) saliva cortisol was measured five times on a single day. Results: Evening cortisol was significantly higher in untreated individuals with DD. Significantly higher evening cortisol (at 22 h) correlated also with a history of physical disorder, a history of any mental disorder and MADRS score ≥ 20 (Montgomery-Åsberg Depression Rating Scale). High cortisol, measured as AUC (area under curve), correlated with a high MADRS score but not with any other health variable tested. Morning cortisol did not correlate with any health variable; however, cortisol awakening response (CAR) could not be investigated. The BDI and GMDS scores did not correlate with cortisol measurements. Conclusion: Evening saliva cortisol measurement seems most informative, as it correlates with male depressive syndrome in our study but replications with larger studies are needed. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Nordic Journal of Psychiatry is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.3109/08039488.2012.704069 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 8 StartPage: 145 Subjects: – SubjectFull: Hydrocortisone Type: general – SubjectFull: Mental depression Type: general – SubjectFull: Hypothalamic-pituitary-adrenal axis Type: general – SubjectFull: Mental health Type: general – SubjectFull: Montgomery (Ala.) Type: general Titles: – TitleFull: Saliva cortisol and male depressive syndrome in a community study. The Sudurnesjamenn study. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Sigurdsson, Bjarni – PersonEntity: Name: NameFull: Palsson, Sigurdur Pall – PersonEntity: Name: NameFull: Johannsson, Magnus – PersonEntity: Name: NameFull: Olafsdottir, Maria – PersonEntity: Name: NameFull: Aevarsson, Olafur IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 06 Text: Jun2013 Type: published Y: 2013 Identifiers: – Type: issn-print Value: 08039488 Numbering: – Type: volume Value: 67 – Type: issue Value: 3 Titles: – TitleFull: Nordic Journal of Psychiatry Type: main |
| ResultId | 1 |
