Bibliographic Details
| Title: |
Production of cytokines following brain injury: beneficial and deleterious for the damaged tissue. |
| Authors: |
Morganti-Kossman, M.C., Lenzlinger, P.M., Hans, V., Stahel, P., Csuka, E., Ammann, E., Stocker, R., Trentz, O., Kossmann, T. |
| Source: |
Molecular Psychiatry. 1997, Vol. 2 Issue 2, p133. 4p. |
| Subjects: |
Brain injuries, Cytokines |
| Abstract: |
A profound inflammatory response is initiated immediately following traumatic brain injury (TBI) and is characterized by the release of several cytokines with pro- and anti-inflammatory functions. In order to elucidate which cytokines are released in the human brain in response to injury as well as in the peripheral compartment, IL-1, IL-6, IL-8, IL-10, TNF-α and TGF-β were monitored in CSF and serum of severely brain-injured patients. Furthermore, we investigated the possible modulation of systemic reactions by IL-6 and the ability of IL-6 and IL-8 to promote the synthesis of nerve growth factor. [ABSTRACT FROM AUTHOR] |
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| Database: |
Psychology and Behavioral Sciences Collection |
