Production of cytokines following brain injury: beneficial and deleterious for the damaged tissue.
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| Title: | Production of cytokines following brain injury: beneficial and deleterious for the damaged tissue. |
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| Authors: | Morganti-Kossman, M.C., Lenzlinger, P.M., Hans, V., Stahel, P., Csuka, E., Ammann, E., Stocker, R., Trentz, O., Kossmann, T. |
| Source: | Molecular Psychiatry. 1997, Vol. 2 Issue 2, p133. 4p. |
| Subjects: | Brain injuries, Cytokines |
| Abstract: | A profound inflammatory response is initiated immediately following traumatic brain injury (TBI) and is characterized by the release of several cytokines with pro- and anti-inflammatory functions. In order to elucidate which cytokines are released in the human brain in response to injury as well as in the peripheral compartment, IL-1, IL-6, IL-8, IL-10, TNF-α and TGF-β were monitored in CSF and serum of severely brain-injured patients. Furthermore, we investigated the possible modulation of systemic reactions by IL-6 and the ability of IL-6 and IL-8 to promote the synthesis of nerve growth factor. [ABSTRACT FROM AUTHOR] |
| Copyright of Molecular Psychiatry is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: pbh DbLabel: Psychology and Behavioral Sciences Collection An: 9012566 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1038/sj.mp.4000227 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 4 StartPage: 133 Subjects: – SubjectFull: Brain injuries Type: general – SubjectFull: Cytokines Type: general Titles: – TitleFull: Production of cytokines following brain injury: beneficial and deleterious for the damaged tissue. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Morganti-Kossman, M.C. – PersonEntity: Name: NameFull: Lenzlinger, P.M. – PersonEntity: Name: NameFull: Hans, V. – PersonEntity: Name: NameFull: Stahel, P. – PersonEntity: Name: NameFull: Csuka, E. – PersonEntity: Name: NameFull: Ammann, E. – PersonEntity: Name: NameFull: Stocker, R. – PersonEntity: Name: NameFull: Trentz, O. – PersonEntity: Name: NameFull: Kossmann, T. IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 03 Text: 1997 Type: published Y: 1997 Identifiers: – Type: issn-print Value: 13594184 Numbering: – Type: volume Value: 2 – Type: issue Value: 2 Titles: – TitleFull: Molecular Psychiatry Type: main |
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