Decreased muscarinic1 receptors in the dorsolateral prefrontal cortex of subjects with schizophrenia.

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Bibliographic Details
Title: Decreased muscarinic1 receptors in the dorsolateral prefrontal cortex of subjects with schizophrenia.
Authors: Dean, B., McLeod, M., Keriakous, D., McKenzie, J., Scarr, E.
Source: Molecular Psychiatry. 2002, Vol. 7 Issue 10, p1083. 9p.
Subjects: Muscarinic receptors, Prefrontal cortex, Schizophrenia
Abstract: Demonstrates that there is a decrease in muscarinic receptors but not muscarinic receptors in the prefrontal cortex from subjects with schizophrenia. Absence of the change in another region of the cortex; Argument that changes in the cholinergic system of the brain are involved in the pathology of schizophrenia.
Database: Psychology and Behavioral Sciences Collection
Description
Abstract:Demonstrates that there is a decrease in muscarinic receptors but not muscarinic receptors in the prefrontal cortex from subjects with schizophrenia. Absence of the change in another region of the cortex; Argument that changes in the cholinergic system of the brain are involved in the pathology of schizophrenia.
ISSN:13594184
DOI:10.1038/sj.mp.4001199