Optical Control of Muscle Function by Transplantation of Stem Cell-Derived Motor Neurons in Mice.

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Bibliographic Details
Title:	Optical Control of Muscle Function by Transplantation of Stem Cell-Derived Motor Neurons in Mice.
Authors:	Bryson, J. Barney, Machado, Carolina Barcellos, Crossley, Martin, Stevenson, Danielle, Bros-Facer, Virginie, Burrone, Juan, Greensmith, Linda, Lieberam, Ivo
Source:	Science (pre-March 2025). 4/4/2014, Vol. 344 Issue 6179, p94-97. 4p.
Subjects:	Motor neurons, Muscle motility, Optical control, Paralysis treatment, Motor neuron diseases, Therapeutics
Abstract:	The article discusses research by the authors into the optical control of muscles in paralyzed mice through the transplantation of motor neurons derived from stem cells. Topics include loss of motor function through central nervous system damage from injury or disease, the process of grafting motor neurons into the sciatic nerve, and the potential of the strategy to be developed to restore muscle function in humans.
Database:	Psychology and Behavioral Sciences Collection

Description
Abstract:	The article discusses research by the authors into the optical control of muscles in paralyzed mice through the transplantation of motor neurons derived from stem cells. Topics include loss of motor function through central nervous system damage from injury or disease, the process of grafting motor neurons into the sciatic nerve, and the potential of the strategy to be developed to restore muscle function in humans.
ISSN:	00368075
DOI:	10.1126/science.1248523