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Optical Control of Muscle Function by Transplantation of Stem Cell-Derived Motor Neurons in Mice.

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Title: Optical Control of Muscle Function by Transplantation of Stem Cell-Derived Motor Neurons in Mice.
Authors: Bryson, J. Barney, Machado, Carolina Barcellos, Crossley, Martin, Stevenson, Danielle, Bros-Facer, Virginie, Burrone, Juan, Greensmith, Linda, Lieberam, Ivo
Source: Science (pre-March 2025). 4/4/2014, Vol. 344 Issue 6179, p94-97. 4p.
Subjects: Motor neurons, Muscle motility, Optical control, Paralysis treatment, Motor neuron diseases, Therapeutics
Abstract: The article discusses research by the authors into the optical control of muscles in paralyzed mice through the transplantation of motor neurons derived from stem cells. Topics include loss of motor function through central nervous system damage from injury or disease, the process of grafting motor neurons into the sciatic nerve, and the potential of the strategy to be developed to restore muscle function in humans.
Database: Psychology and Behavioral Sciences Collection
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DbLabel: Psychology and Behavioral Sciences Collection
An: 95606523
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
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  Data: Optical Control of Muscle Function by Transplantation of Stem Cell-Derived Motor Neurons in Mice.
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  Data: <searchLink fieldCode="AR" term="%22Bryson%2C+J%2E+Barney%22">Bryson, J. Barney</searchLink><br /><searchLink fieldCode="AR" term="%22Machado%2C+Carolina+Barcellos%22">Machado, Carolina Barcellos</searchLink><br /><searchLink fieldCode="AR" term="%22Crossley%2C+Martin%22">Crossley, Martin</searchLink><br /><searchLink fieldCode="AR" term="%22Stevenson%2C+Danielle%22">Stevenson, Danielle</searchLink><br /><searchLink fieldCode="AR" term="%22Bros-Facer%2C+Virginie%22">Bros-Facer, Virginie</searchLink><br /><searchLink fieldCode="AR" term="%22Burrone%2C+Juan%22">Burrone, Juan</searchLink><br /><searchLink fieldCode="AR" term="%22Greensmith%2C+Linda%22">Greensmith, Linda</searchLink><br /><searchLink fieldCode="AR" term="%22Lieberam%2C+Ivo%22">Lieberam, Ivo</searchLink>
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  Data: <searchLink fieldCode="JN" term="%22Science+%28pre-March+2025%29%22">Science (pre-March 2025)</searchLink>. 4/4/2014, Vol. 344 Issue 6179, p94-97. 4p.
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  Data: <searchLink fieldCode="DE" term="%22Motor+neurons%22">Motor neurons</searchLink><br /><searchLink fieldCode="DE" term="%22Muscle+motility%22">Muscle motility</searchLink><br /><searchLink fieldCode="DE" term="%22Optical+control%22">Optical control</searchLink><br /><searchLink fieldCode="DE" term="%22Paralysis+treatment%22">Paralysis treatment</searchLink><br /><searchLink fieldCode="DE" term="%22Motor+neuron+diseases%22">Motor neuron diseases</searchLink><br /><searchLink fieldCode="DE" term="%22Therapeutics%22">Therapeutics</searchLink>
– Name: Abstract
  Label: Abstract
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  Data: The article discusses research by the authors into the optical control of muscles in paralyzed mice through the transplantation of motor neurons derived from stem cells. Topics include loss of motor function through central nervous system damage from injury or disease, the process of grafting motor neurons into the sciatic nerve, and the potential of the strategy to be developed to restore muscle function in humans.
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=95606523
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      – Type: doi
        Value: 10.1126/science.1248523
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      – Code: eng
        Text: English
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        PageCount: 4
        StartPage: 94
    Subjects:
      – SubjectFull: Motor neurons
        Type: general
      – SubjectFull: Muscle motility
        Type: general
      – SubjectFull: Optical control
        Type: general
      – SubjectFull: Paralysis treatment
        Type: general
      – SubjectFull: Motor neuron diseases
        Type: general
      – SubjectFull: Therapeutics
        Type: general
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      – TitleFull: Optical Control of Muscle Function by Transplantation of Stem Cell-Derived Motor Neurons in Mice.
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            NameFull: Machado, Carolina Barcellos
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            NameFull: Crossley, Martin
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            NameFull: Burrone, Juan
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            NameFull: Greensmith, Linda
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            NameFull: Lieberam, Ivo
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            – D: 04
              M: 04
              Text: 4/4/2014
              Type: published
              Y: 2014
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              Value: 00368075
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              Value: 344
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              Value: 6179
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            – TitleFull: Science (pre-March 2025)
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