Bibliographic Details
| Title: |
Sequestration of a two-component response regulator by a riboswitch-regulated noncoding RNA. |
| Authors: |
Mellin, J. R., Koutero, Mikael, Dar, Daniel, Nahori, Marie-Anne, Sorek, Rotem, Cossart, Pascale |
| Source: |
Science (pre-March 2025). 8/22/2014, Vol. 345 Issue 6199, p940-943. 4p. |
| Subjects: |
Riboswitches, Non-coding RNA, Sequestration (Chemistry), Listeria monocytogenes, Gene expression, Cofactors (Biochemistry), Vitamin B12, Ethanolamines |
| Abstract: |
The article focuses on riboswitch-regulated noncoding RNA's role in sequestration of a two-component response regulator in Listeria monocytogenes. It states that in Listeria, a riboswitch which binds cobalamin controls the expression of the noncoding regulatory RNA Rli55 which in turn controls expression of the eut genes and requires cobalamin as a cofactor to enable ethanolamine utilization. It comments on the role of Rli55 in sequestering proteins in bacterial gene regulation. |
| Database: |
Psychology and Behavioral Sciences Collection |