Sequestration of a two-component response regulator by a riboswitch-regulated noncoding RNA.

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Title: Sequestration of a two-component response regulator by a riboswitch-regulated noncoding RNA.
Authors: Mellin, J. R., Koutero, Mikael, Dar, Daniel, Nahori, Marie-Anne, Sorek, Rotem, Cossart, Pascale
Source: Science (pre-March 2025). 8/22/2014, Vol. 345 Issue 6199, p940-943. 4p.
Subjects: Riboswitches, Non-coding RNA, Sequestration (Chemistry), Listeria monocytogenes, Gene expression, Cofactors (Biochemistry), Vitamin B12, Ethanolamines
Abstract: The article focuses on riboswitch-regulated noncoding RNA's role in sequestration of a two-component response regulator in Listeria monocytogenes. It states that in Listeria, a riboswitch which binds cobalamin controls the expression of the noncoding regulatory RNA Rli55 which in turn controls expression of the eut genes and requires cobalamin as a cofactor to enable ethanolamine utilization. It comments on the role of Rli55 in sequestering proteins in bacterial gene regulation.
Database: Psychology and Behavioral Sciences Collection
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DbLabel: Psychology and Behavioral Sciences Collection
An: 97746974
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PubType: Academic Journal
PubTypeId: academicJournal
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Items – Name: Title
  Label: Title
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  Data: Sequestration of a two-component response regulator by a riboswitch-regulated noncoding RNA.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Mellin%2C+J%2E+R%2E%22">Mellin, J. R.</searchLink><br /><searchLink fieldCode="AR" term="%22Koutero%2C+Mikael%22">Koutero, Mikael</searchLink><br /><searchLink fieldCode="AR" term="%22Dar%2C+Daniel%22">Dar, Daniel</searchLink><br /><searchLink fieldCode="AR" term="%22Nahori%2C+Marie-Anne%22">Nahori, Marie-Anne</searchLink><br /><searchLink fieldCode="AR" term="%22Sorek%2C+Rotem%22">Sorek, Rotem</searchLink><br /><searchLink fieldCode="AR" term="%22Cossart%2C+Pascale%22">Cossart, Pascale</searchLink>
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  Data: <searchLink fieldCode="JN" term="%22Science+%28pre-March+2025%29%22">Science (pre-March 2025)</searchLink>. 8/22/2014, Vol. 345 Issue 6199, p940-943. 4p.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22Riboswitches%22">Riboswitches</searchLink><br /><searchLink fieldCode="DE" term="%22Non-coding+RNA%22">Non-coding RNA</searchLink><br /><searchLink fieldCode="DE" term="%22Sequestration+%28Chemistry%29%22">Sequestration (Chemistry)</searchLink><br /><searchLink fieldCode="DE" term="%22Listeria+monocytogenes%22">Listeria monocytogenes</searchLink><br /><searchLink fieldCode="DE" term="%22Gene+expression%22">Gene expression</searchLink><br /><searchLink fieldCode="DE" term="%22Cofactors+%28Biochemistry%29%22">Cofactors (Biochemistry)</searchLink><br /><searchLink fieldCode="DE" term="%22Vitamin+B12%22">Vitamin B12</searchLink><br /><searchLink fieldCode="DE" term="%22Ethanolamines%22">Ethanolamines</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: The article focuses on riboswitch-regulated noncoding RNA's role in sequestration of a two-component response regulator in Listeria monocytogenes. It states that in Listeria, a riboswitch which binds cobalamin controls the expression of the noncoding regulatory RNA Rli55 which in turn controls expression of the eut genes and requires cobalamin as a cofactor to enable ethanolamine utilization. It comments on the role of Rli55 in sequestering proteins in bacterial gene regulation.
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RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1126/science.1255083
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 4
        StartPage: 940
    Subjects:
      – SubjectFull: Riboswitches
        Type: general
      – SubjectFull: Non-coding RNA
        Type: general
      – SubjectFull: Sequestration (Chemistry)
        Type: general
      – SubjectFull: Listeria monocytogenes
        Type: general
      – SubjectFull: Gene expression
        Type: general
      – SubjectFull: Cofactors (Biochemistry)
        Type: general
      – SubjectFull: Vitamin B12
        Type: general
      – SubjectFull: Ethanolamines
        Type: general
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      – TitleFull: Sequestration of a two-component response regulator by a riboswitch-regulated noncoding RNA.
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            NameFull: Mellin, J. R.
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            NameFull: Koutero, Mikael
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            NameFull: Dar, Daniel
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            NameFull: Nahori, Marie-Anne
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            NameFull: Sorek, Rotem
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            NameFull: Cossart, Pascale
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            – D: 22
              M: 08
              Text: 8/22/2014
              Type: published
              Y: 2014
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              Value: 00368075
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              Value: 345
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              Value: 6199
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            – TitleFull: Science (pre-March 2025)
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