The relationship between living arrangement and adherence to antiepileptic medications among individuals with developmental disabilities.
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| Title: | The relationship between living arrangement and adherence to antiepileptic medications among individuals with developmental disabilities. |
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| Authors: | Hom, C. L., Touchette, P., Nguyen, V., Fernandez, G., Tournay, A., Plon, L., Himber, P., Lott, I. T. |
| Source: | Journal of Intellectual Disability Research. Jan2015, Vol. 59 Issue 1, p48-54. 7p. 3 Charts. |
| Subjects: | Adults, Anticonvulsants, Confidence intervals, Drugs, People with intellectual disabilities, Patient compliance, Statistics, Logistic regression analysis, Data analysis, Residential patterns, Residential care, Independent living, Descriptive statistics, Odds ratio |
| Abstract: | Background Non-adherence to antiepileptic drugs ( AEDs) is associated with considerable morbidity and mortality in the general population but little is known about adherence in individuals with intellectual disability ( ID). Method Using the records of a closed pharmacy billing system over a 30 month period, we examined the medication non-adherence rates for AEDs among 793 individuals with ID. We calculated the medication possession ratio (number of days each participant was in possession of an AED), and defined non-adherence as 25% or more of the exposure days without the possession of an AED. All participants studied had filled prescriptions for AEDs spanning at least 6 months. Results Controlling for age and gender, we found non-adherence rates varied by living arrangement. Compared with those living in group homes, individuals with ID living in family homes or in semi-independent settings were significantly less adherent to AEDs ( P < 0.0003). Conclusion Non-adherence to AEDs is a potential medical risk for individuals with ID that is significantly impacted by the type of community living arrangement. [ABSTRACT FROM AUTHOR] |
| Copyright of Journal of Intellectual Disability Research is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
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| Abstract: | Background Non-adherence to antiepileptic drugs ( AEDs) is associated with considerable morbidity and mortality in the general population but little is known about adherence in individuals with intellectual disability ( ID). Method Using the records of a closed pharmacy billing system over a 30 month period, we examined the medication non-adherence rates for AEDs among 793 individuals with ID. We calculated the medication possession ratio (number of days each participant was in possession of an AED), and defined non-adherence as 25% or more of the exposure days without the possession of an AED. All participants studied had filled prescriptions for AEDs spanning at least 6 months. Results Controlling for age and gender, we found non-adherence rates varied by living arrangement. Compared with those living in group homes, individuals with ID living in family homes or in semi-independent settings were significantly less adherent to AEDs ( P < 0.0003). Conclusion Non-adherence to AEDs is a potential medical risk for individuals with ID that is significantly impacted by the type of community living arrangement. [ABSTRACT FROM AUTHOR] |
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| ISSN: | 09642633 |
| DOI: | 10.1111/jir.12123 |
