ABBV-712-induced cardiac pathology in rats is related to off-target-driven acute vasodilation, tachycardia, and increased cardiac contractility.

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Bibliographic Details
Title: ABBV-712-induced cardiac pathology in rats is related to off-target-driven acute vasodilation, tachycardia, and increased cardiac contractility.
Authors: Kohnken, Rebecca1 (AUTHOR), Fossey, Stacey2 (AUTHOR), Buck, Wayne R2 (AUTHOR), Segreti, Jason1 (AUTHOR), Treadway, Jessica1 (AUTHOR), Green, Jonathon1 (AUTHOR), Koshman, Yevgeniya E2 (AUTHOR), Zafiratos, Mark1 (AUTHOR), Mittelstadt, Scott3 (AUTHOR), Blomme, Eric4 (AUTHOR), Foley, Charles M1 (AUTHOR)
Source: Toxicological Sciences. May2025, Vol. 205 Issue 1, p233-244. 12p.
Database: Environment Complete
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ISSN:10966080
DOI:10.1093/toxsci/kfaf021