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HUWE1 is a critical colonic tumour suppressor gene that prevents MYC signalling, DNA damage accumulation and tumour initiation.

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Title: HUWE1 is a critical colonic tumour suppressor gene that prevents MYC signalling, DNA damage accumulation and tumour initiation.
Authors: Myant KB; Cancer Research UK Beatson Institute, Garscube Estate, Bearsden, Glasgow, UK kevin.myant@igmm.ed.ac.uk o.sansom@beatson.gla.ac.uk.; Cancer Research UK Edinburgh Centre, The Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, UK., Cammareri P; Cancer Research UK Beatson Institute, Garscube Estate, Bearsden, Glasgow, UK., Hodder MC; Cancer Research UK Beatson Institute, Garscube Estate, Bearsden, Glasgow, UK., Wills J; Cancer Research UK Edinburgh Centre, The Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, UK., Von Kriegsheim A; Cancer Research UK Edinburgh Centre, The Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, UK., Győrffy B; MTA TTK Lendület Cancer Biomarker Research Group, Budapest, Hungary.; 2nd Department of Pediatrics, Semmelweis University, Budapest, Hungary., Rashid M; Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK., Polo S; IFOM, The FIRC Institute for Molecular Oncology, Milano, Italy., Maspero E; IFOM, The FIRC Institute for Molecular Oncology, Milano, Italy., Vaughan L; Cancer Research UK Manchester Institute, The University of Manchester, Withington, Manchester, UK., Gurung B; Boston Children's Hospital, Boston, MA, USA., Barry E; Boston Children's Hospital, Boston, MA, USA., Malliri A; Cancer Research UK Manchester Institute, The University of Manchester, Withington, Manchester, UK., Camargo F; Boston Children's Hospital, Boston, MA, USA., Adams DJ; Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK., Iavarone A; Departments of Neurology and Pathology, Institute for Cancer Genetics, Irving Comprehensive Research Center, New York, NY, USA., Lasorella A; Departments of Pediatrics and Pathology, Institute for Cancer Genetics, Irving Comprehensive Research Center, New York, NY, USA., Sansom OJ; Cancer Research UK Beatson Institute, Garscube Estate, Bearsden, Glasgow, UK kevin.myant@igmm.ed.ac.uk o.sansom@beatson.gla.ac.uk.
Source: EMBO molecular medicine [EMBO Mol Med] 2017 Feb; Vol. 9 (2), pp. 181-197.
Publication Type: Journal Article
Journal Info: Publisher: EMBO Press Country of Publication: Germany NLM ID: 101487380 Publication Model: Print Cited Medium: Internet ISSN: 1757-4684 (Electronic) Linking ISSN: 17574676 NLM ISO Abbreviation: EMBO Mol Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: HUWE1 is a critical colonic tumour suppressor gene that prevents MYC signalling, DNA damage accumulation and tumour initiation.
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  Data: <searchLink fieldCode="AU" term="%22Myant+KB%22">Myant KB</searchLink>; Cancer Research UK Beatson Institute, Garscube Estate, Bearsden, Glasgow, UK kevin.myant@igmm.ed.ac.uk o.sansom@beatson.gla.ac.uk.; Cancer Research UK Edinburgh Centre, The Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Cammareri+P%22">Cammareri P</searchLink>; Cancer Research UK Beatson Institute, Garscube Estate, Bearsden, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Hodder+MC%22">Hodder MC</searchLink>; Cancer Research UK Beatson Institute, Garscube Estate, Bearsden, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Wills+J%22">Wills J</searchLink>; Cancer Research UK Edinburgh Centre, The Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Von+Kriegsheim+A%22">Von Kriegsheim A</searchLink>; Cancer Research UK Edinburgh Centre, The Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Győrffy+B%22">Győrffy B</searchLink>; MTA TTK Lendület Cancer Biomarker Research Group, Budapest, Hungary.; 2nd Department of Pediatrics, Semmelweis University, Budapest, Hungary.<br /><searchLink fieldCode="AU" term="%22Rashid+M%22">Rashid M</searchLink>; Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Polo+S%22">Polo S</searchLink>; IFOM, The FIRC Institute for Molecular Oncology, Milano, Italy.<br /><searchLink fieldCode="AU" term="%22Maspero+E%22">Maspero E</searchLink>; IFOM, The FIRC Institute for Molecular Oncology, Milano, Italy.<br /><searchLink fieldCode="AU" term="%22Vaughan+L%22">Vaughan L</searchLink>; Cancer Research UK Manchester Institute, The University of Manchester, Withington, Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Gurung+B%22">Gurung B</searchLink>; Boston Children's Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Barry+E%22">Barry E</searchLink>; Boston Children's Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Malliri+A%22">Malliri A</searchLink>; Cancer Research UK Manchester Institute, The University of Manchester, Withington, Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Camargo+F%22">Camargo F</searchLink>; Boston Children's Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Adams+DJ%22">Adams DJ</searchLink>; Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Iavarone+A%22">Iavarone A</searchLink>; Departments of Neurology and Pathology, Institute for Cancer Genetics, Irving Comprehensive Research Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Lasorella+A%22">Lasorella A</searchLink>; Departments of Pediatrics and Pathology, Institute for Cancer Genetics, Irving Comprehensive Research Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Sansom+OJ%22">Sansom OJ</searchLink>; Cancer Research UK Beatson Institute, Garscube Estate, Bearsden, Glasgow, UK kevin.myant@igmm.ed.ac.uk o.sansom@beatson.gla.ac.uk.
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