View in EDS

Control of phosphorothioate stereochemistry substantially increases the efficacy of antisense oligonucleotides.

Saved in:
Bibliographic Details
Title: Control of phosphorothioate stereochemistry substantially increases the efficacy of antisense oligonucleotides.
Authors: Iwamoto N; Wave Life Sciences, Cambridge, Massachusetts, USA., Butler DCD; Wave Life Sciences, Cambridge, Massachusetts, USA., Svrzikapa N; Wave Life Sciences, Cambridge, Massachusetts, USA., Mohapatra S; Wave Life Sciences, Cambridge, Massachusetts, USA., Zlatev I; Wave Life Sciences, Cambridge, Massachusetts, USA., Sah DWY; Wave Life Sciences, Cambridge, Massachusetts, USA., Meena; Wave Life Sciences, Cambridge, Massachusetts, USA., Standley SM; Wave Life Sciences, Cambridge, Massachusetts, USA., Lu G; Wave Life Sciences, Cambridge, Massachusetts, USA., Apponi LH; Wave Life Sciences, Cambridge, Massachusetts, USA., Frank-Kamenetsky M; Wave Life Sciences, Cambridge, Massachusetts, USA., Zhang JJ; Wave Life Sciences, Cambridge, Massachusetts, USA., Vargeese C; Wave Life Sciences, Cambridge, Massachusetts, USA., Verdine GL; Wave Life Sciences, Cambridge, Massachusetts, USA.; Department of Stem Cell and Regenerative Biology, Department of Chemistry and Chemical Biology, Harvard University and Harvard Medical School, Cambridge, Massachusetts, USA.
Source: Nature biotechnology [Nat Biotechnol] 2017 Sep; Vol. 35 (9), pp. 845-851. Date of Electronic Publication: 2017 Aug 21.
Publication Type: Journal Article
Journal Info: Publisher: Nature America Publishing Country of Publication: United States NLM ID: 9604648 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1696 (Electronic) Linking ISSN: 10870156 NLM ISO Abbreviation: Nat Biotechnol Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 28829437
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Control of phosphorothioate stereochemistry substantially increases the efficacy of antisense oligonucleotides.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Iwamoto+N%22">Iwamoto N</searchLink>; Wave Life Sciences, Cambridge, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Butler+DCD%22">Butler DCD</searchLink>; Wave Life Sciences, Cambridge, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Svrzikapa+N%22">Svrzikapa N</searchLink>; Wave Life Sciences, Cambridge, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Mohapatra+S%22">Mohapatra S</searchLink>; Wave Life Sciences, Cambridge, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Zlatev+I%22">Zlatev I</searchLink>; Wave Life Sciences, Cambridge, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Sah+DWY%22">Sah DWY</searchLink>; Wave Life Sciences, Cambridge, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Meena%22">Meena</searchLink>; Wave Life Sciences, Cambridge, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Standley+SM%22">Standley SM</searchLink>; Wave Life Sciences, Cambridge, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Lu+G%22">Lu G</searchLink>; Wave Life Sciences, Cambridge, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Apponi+LH%22">Apponi LH</searchLink>; Wave Life Sciences, Cambridge, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Frank-Kamenetsky+M%22">Frank-Kamenetsky M</searchLink>; Wave Life Sciences, Cambridge, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+JJ%22">Zhang JJ</searchLink>; Wave Life Sciences, Cambridge, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Vargeese+C%22">Vargeese C</searchLink>; Wave Life Sciences, Cambridge, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Verdine+GL%22">Verdine GL</searchLink>; Wave Life Sciences, Cambridge, Massachusetts, USA.; Department of Stem Cell and Regenerative Biology, Department of Chemistry and Chemical Biology, Harvard University and Harvard Medical School, Cambridge, Massachusetts, USA.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%229604648%22">Nature biotechnology</searchLink> [Nat Biotechnol] 2017 Sep; Vol. 35 (9), pp. 845-851. <i>Date of Electronic Publication: </i>2017 Aug 21.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+America+Publishing%22">Nature America Publishing </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9604648 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1546-1696 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210870156%22">10870156 </searchLink><i>NLM ISO Abbreviation: </i>Nat Biotechnol <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=28829437
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1038/nbt.3948
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 845
    Titles:
      – TitleFull: Control of phosphorothioate stereochemistry substantially increases the efficacy of antisense oligonucleotides.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Iwamoto N
      – PersonEntity:
          Name:
            NameFull: Butler DCD
      – PersonEntity:
          Name:
            NameFull: Svrzikapa N
      – PersonEntity:
          Name:
            NameFull: Mohapatra S
      – PersonEntity:
          Name:
            NameFull: Zlatev I
      – PersonEntity:
          Name:
            NameFull: Sah DWY
      – PersonEntity:
          Name:
            NameFull: Meena
      – PersonEntity:
          Name:
            NameFull: Standley SM
      – PersonEntity:
          Name:
            NameFull: Lu G
      – PersonEntity:
          Name:
            NameFull: Apponi LH
      – PersonEntity:
          Name:
            NameFull: Frank-Kamenetsky M
      – PersonEntity:
          Name:
            NameFull: Zhang JJ
      – PersonEntity:
          Name:
            NameFull: Vargeese C
      – PersonEntity:
          Name:
            NameFull: Verdine GL
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 09
              Text: 2017 Sep
              Type: published
              Y: 2017
          Identifiers:
            – Type: issn-electronic
              Value: 1546-1696
          Numbering:
            – Type: volume
              Value: 35
            – Type: issue
              Value: 9
          Titles:
            – TitleFull: Nature biotechnology
              Type: main
ResultId 1