Chemical Instability and Promiscuity of Arylmethylidenepyrazolinone-Based MDMX Inhibitors.
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| Title: | Chemical Instability and Promiscuity of Arylmethylidenepyrazolinone-Based MDMX Inhibitors. |
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| Authors: | Stefaniak J; Structural Genomics Consortium, Nuffield Department of Medicine , University of Oxford , Oxford , United Kingdom.; Target Discovery Institute, Nuffield Department of Medicine , University of Oxford , Oxford , United Kingdom.; Department of Chemistry, Chemistry Research Laboratory , University of Oxford , Oxford , United Kingdom., Lewis AM; Structural Genomics Consortium, Nuffield Department of Medicine , University of Oxford , Oxford , United Kingdom.; Target Discovery Institute, Nuffield Department of Medicine , University of Oxford , Oxford , United Kingdom., Conole D; Department of Chemistry, Chemistry Research Laboratory , University of Oxford , Oxford , United Kingdom., Galan SRG; Department of Chemistry, Chemistry Research Laboratory , University of Oxford , Oxford , United Kingdom., Bataille CJR; Department of Chemistry, Chemistry Research Laboratory , University of Oxford , Oxford , United Kingdom., Wynne GM; Department of Chemistry, Chemistry Research Laboratory , University of Oxford , Oxford , United Kingdom.; Department of Pharmacology , University of Oxford , Oxford , United Kingdom., Castaldi MP; Discovery Sciences, IMED Biotech Unit , AstraZeneca , Waltham , Massachusetts 02451 , United States., Lundbäck T; Discovery Sciences, IMED Biotech Unit , AstraZeneca , Gothenburg , Sweden., Russell AJ; Department of Chemistry, Chemistry Research Laboratory , University of Oxford , Oxford , United Kingdom.; Department of Pharmacology , University of Oxford , Oxford , United Kingdom., Huber KVM; Structural Genomics Consortium, Nuffield Department of Medicine , University of Oxford , Oxford , United Kingdom.; Target Discovery Institute, Nuffield Department of Medicine , University of Oxford , Oxford , United Kingdom. |
| Source: | ACS chemical biology [ACS Chem Biol] 2018 Oct 19; Vol. 13 (10), pp. 2849-2854. Date of Electronic Publication: 2018 Sep 19. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: American Chemical Society Country of Publication: United States NLM ID: 101282906 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1554-8937 (Electronic) Linking ISSN: 15548929 NLM ISO Abbreviation: ACS Chem Biol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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