Targeting all transforming growth factor-β isoforms with an Fc chimeric receptor impairs tumor growth and angiogenesis of oral squamous cell cancer.

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Title: Targeting all transforming growth factor-β isoforms with an Fc chimeric receptor impairs tumor growth and angiogenesis of oral squamous cell cancer.
Authors: Takahashi K; Department of Biochemistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan., Akatsu Y; Department of Molecular Pathology, Graduate School of Medicine, the University of Tokyo, Tokyo, Japan.; Biomedicine Group, Pharmaceutical Research Laboratories, and Pharmaceutical Group, Nippon Kayaku Co. Ltd., Tokyo, Japan., Podyma-Inoue KA; Department of Biochemistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan., Matsumoto T; RIKEN Center for Biosystems Dynamics Research, Yokohama, Japan., Takahashi H; Department of Biochemistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan., Yoshimatsu Y; Department of Biochemistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan.; Division of Pharmacology, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan., Koinuma D; Department of Molecular Pathology, Graduate School of Medicine, the University of Tokyo, Tokyo, Japan., Shirouzu M; RIKEN Center for Biosystems Dynamics Research, Yokohama, Japan., Miyazono K; Department of Molecular Pathology, Graduate School of Medicine, the University of Tokyo, Tokyo, Japan., Watabe T; Department of Biochemistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan t-watabe@umin.ac.jp.
Source: The Journal of biological chemistry [J Biol Chem] 2020 Sep 04; Vol. 295 (36), pp. 12559-12572. Date of Electronic Publication: 2020 Jul 06.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Targeting all transforming growth factor-β isoforms with an Fc chimeric receptor impairs tumor growth and angiogenesis of oral squamous cell cancer.
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  Data: <searchLink fieldCode="AU" term="%22Takahashi+K%22">Takahashi K</searchLink>; Department of Biochemistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Akatsu+Y%22">Akatsu Y</searchLink>; Department of Molecular Pathology, Graduate School of Medicine, the University of Tokyo, Tokyo, Japan.; Biomedicine Group, Pharmaceutical Research Laboratories, and Pharmaceutical Group, Nippon Kayaku Co. Ltd., Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Podyma-Inoue+KA%22">Podyma-Inoue KA</searchLink>; Department of Biochemistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Matsumoto+T%22">Matsumoto T</searchLink>; RIKEN Center for Biosystems Dynamics Research, Yokohama, Japan.<br /><searchLink fieldCode="AU" term="%22Takahashi+H%22">Takahashi H</searchLink>; Department of Biochemistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Yoshimatsu+Y%22">Yoshimatsu Y</searchLink>; Department of Biochemistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan.; Division of Pharmacology, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan.<br /><searchLink fieldCode="AU" term="%22Koinuma+D%22">Koinuma D</searchLink>; Department of Molecular Pathology, Graduate School of Medicine, the University of Tokyo, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Shirouzu+M%22">Shirouzu M</searchLink>; RIKEN Center for Biosystems Dynamics Research, Yokohama, Japan.<br /><searchLink fieldCode="AU" term="%22Miyazono+K%22">Miyazono K</searchLink>; Department of Molecular Pathology, Graduate School of Medicine, the University of Tokyo, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Watabe+T%22">Watabe T</searchLink>; Department of Biochemistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan t-watabe@umin.ac.jp.
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  Data: <searchLink fieldCode="JN" term="%222985121R%22">The Journal of biological chemistry</searchLink> [J Biol Chem] 2020 Sep 04; Vol. 295 (36), pp. 12559-12572. <i>Date of Electronic Publication: </i>2020 Jul 06.
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  Data: Journal Article; Research Support, Non-U.S. Gov't
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Inc%2E+on+behalf+of+American+Society+for+Biochemistry+and+Molecular+Biology%22">Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>2985121R <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1083-351X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200219258%22">00219258 </searchLink><i>NLM ISO Abbreviation: </i>J Biol Chem <i>Subsets: </i>MEDLINE
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        Value: 10.1074/jbc.RA120.012492
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              Text: 2020 Sep 04
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