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Endogenous Retroelement Activation by Epigenetic Therapy Reverses the Warburg Effect and Elicits Mitochondrial-Mediated Cancer Cell Death.

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Title: Endogenous Retroelement Activation by Epigenetic Therapy Reverses the Warburg Effect and Elicits Mitochondrial-Mediated Cancer Cell Death.
Authors: Fresquet V; Division of Hematology, Center for Applied Medical Research CIMA, University of Navarra, IDISNA, CIBERONC, Pamplona, Spain. jamcliment@unav.es vfresquet@unav.es., Garcia-Barchino MJ; Division of Hematology, Center for Applied Medical Research CIMA, University of Navarra, IDISNA, CIBERONC, Pamplona, Spain., Larrayoz M; Division of Hematology, Center for Applied Medical Research CIMA, University of Navarra, IDISNA, CIBERONC, Pamplona, Spain., Celay J; Division of Hematology, Center for Applied Medical Research CIMA, University of Navarra, IDISNA, CIBERONC, Pamplona, Spain., Vicente C; Division of Hematology, Center for Applied Medical Research CIMA, University of Navarra, IDISNA, CIBERONC, Pamplona, Spain., Fernandez-Galilea M; Division of Hematology, Center for Applied Medical Research CIMA, University of Navarra, IDISNA, CIBERONC, Pamplona, Spain.; Center for Nutrition Research and Department of Nutrition, Food Science and Physiology, University of Navarra, IDISNA, CIBEROBN, Pamplona, Spain., Larrayoz MJ; Division of Hematology, Center for Applied Medical Research CIMA, University of Navarra, IDISNA, CIBERONC, Pamplona, Spain., Calasanz MJ; Division of Hematology, Center for Applied Medical Research CIMA, University of Navarra, IDISNA, CIBERONC, Pamplona, Spain., Panizo C; Department of Hematology, Clinica Universidad de Navarra, University of Navarra, IDISNA, CIBERONC, Pamplona, Spain., Junza A; Universitat Rovira i Virgili, Department of Electronic Engineering, IISPV, CIBERDEM, Tarragona, Spain., Han J; State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, Fujian, China., Prior C; Division of Gene Therapy and Hepatology, Center for Applied Medical Research CIMA, University of Navarra, IDISNA, CIBEREHD, Pamplona, Spain., Fortes P; Division of Gene Therapy and Hepatology, Center for Applied Medical Research CIMA, University of Navarra, IDISNA, CIBEREHD, Pamplona, Spain., Pio R; Division of Solid Tumors, Center for Applied Medical Research CIMA, University of Navarra, IDISNA, CIBERONC, Pamplona, Spain., Oyarzabal J; Division of Molecular Therapeutics, Center for Applied Medical Research CIMA, University of Navarra, IDISNA, Pamplona, Spain., Martinez-Baztan A; Division of Hematology, Center for Applied Medical Research CIMA, University of Navarra, IDISNA, CIBERONC, Pamplona, Spain., Paiva B; Division of Hematology, Center for Applied Medical Research CIMA, University of Navarra, IDISNA, CIBERONC, Pamplona, Spain., Moreno-Aliaga MJ; Center for Nutrition Research and Department of Nutrition, Food Science and Physiology, University of Navarra, IDISNA, CIBEROBN, Pamplona, Spain., Odero MD; Division of Hematology, Center for Applied Medical Research CIMA, University of Navarra, IDISNA, CIBERONC, Pamplona, Spain., Agirre X; Division of Hematology, Center for Applied Medical Research CIMA, University of Navarra, IDISNA, CIBERONC, Pamplona, Spain., Yanes O; Universitat Rovira i Virgili, Department of Electronic Engineering, IISPV, CIBERDEM, Tarragona, Spain., Prosper F; Division of Hematology, Center for Applied Medical Research CIMA, University of Navarra, IDISNA, CIBERONC, Pamplona, Spain.; Department of Hematology, Clinica Universidad de Navarra, University of Navarra, IDISNA, CIBERONC, Pamplona, Spain., Martinez-Climent JA; Division of Hematology, Center for Applied Medical Research CIMA, University of Navarra, IDISNA, CIBERONC, Pamplona, Spain. jamcliment@unav.es vfresquet@unav.es.
Source: Cancer discovery [Cancer Discov] 2021 May; Vol. 11 (5), pp. 1268-1285. Date of Electronic Publication: 2020 Dec 18.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101561693 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2159-8290 (Electronic) Linking ISSN: 21598274 NLM ISO Abbreviation: Cancer Discov Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: Endogenous Retroelement Activation by Epigenetic Therapy Reverses the Warburg Effect and Elicits Mitochondrial-Mediated Cancer Cell Death.
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  Data: <searchLink fieldCode="AU" term="%22Fresquet+V%22">Fresquet V</searchLink>; Division of Hematology, Center for Applied Medical Research CIMA, University of Navarra, IDISNA, CIBERONC, Pamplona, Spain. jamcliment@unav.es vfresquet@unav.es.<br /><searchLink fieldCode="AU" term="%22Garcia-Barchino+MJ%22">Garcia-Barchino MJ</searchLink>; Division of Hematology, Center for Applied Medical Research CIMA, University of Navarra, IDISNA, CIBERONC, Pamplona, Spain.<br /><searchLink fieldCode="AU" term="%22Larrayoz+M%22">Larrayoz M</searchLink>; Division of Hematology, Center for Applied Medical Research CIMA, University of Navarra, IDISNA, CIBERONC, Pamplona, Spain.<br /><searchLink fieldCode="AU" term="%22Celay+J%22">Celay J</searchLink>; Division of Hematology, Center for Applied Medical Research CIMA, University of Navarra, IDISNA, CIBERONC, Pamplona, Spain.<br /><searchLink fieldCode="AU" term="%22Vicente+C%22">Vicente C</searchLink>; Division of Hematology, Center for Applied Medical Research CIMA, University of Navarra, IDISNA, CIBERONC, Pamplona, Spain.<br /><searchLink fieldCode="AU" term="%22Fernandez-Galilea+M%22">Fernandez-Galilea M</searchLink>; Division of Hematology, Center for Applied Medical Research CIMA, University of Navarra, IDISNA, CIBERONC, Pamplona, Spain.; Center for Nutrition Research and Department of Nutrition, Food Science and Physiology, University of Navarra, IDISNA, CIBEROBN, Pamplona, Spain.<br /><searchLink fieldCode="AU" term="%22Larrayoz+MJ%22">Larrayoz MJ</searchLink>; Division of Hematology, Center for Applied Medical Research CIMA, University of Navarra, IDISNA, CIBERONC, Pamplona, Spain.<br /><searchLink fieldCode="AU" term="%22Calasanz+MJ%22">Calasanz MJ</searchLink>; Division of Hematology, Center for Applied Medical Research CIMA, University of Navarra, IDISNA, CIBERONC, Pamplona, Spain.<br /><searchLink fieldCode="AU" term="%22Panizo+C%22">Panizo C</searchLink>; Department of Hematology, Clinica Universidad de Navarra, University of Navarra, IDISNA, CIBERONC, Pamplona, Spain.<br /><searchLink fieldCode="AU" term="%22Junza+A%22">Junza A</searchLink>; Universitat Rovira i Virgili, Department of Electronic Engineering, IISPV, CIBERDEM, Tarragona, Spain.<br /><searchLink fieldCode="AU" term="%22Han+J%22">Han J</searchLink>; State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, Fujian, China.<br /><searchLink fieldCode="AU" term="%22Prior+C%22">Prior C</searchLink>; Division of Gene Therapy and Hepatology, Center for Applied Medical Research CIMA, University of Navarra, IDISNA, CIBEREHD, Pamplona, Spain.<br /><searchLink fieldCode="AU" term="%22Fortes+P%22">Fortes P</searchLink>; Division of Gene Therapy and Hepatology, Center for Applied Medical Research CIMA, University of Navarra, IDISNA, CIBEREHD, Pamplona, Spain.<br /><searchLink fieldCode="AU" term="%22Pio+R%22">Pio R</searchLink>; Division of Solid Tumors, Center for Applied Medical Research CIMA, University of Navarra, IDISNA, CIBERONC, Pamplona, Spain.<br /><searchLink fieldCode="AU" term="%22Oyarzabal+J%22">Oyarzabal J</searchLink>; Division of Molecular Therapeutics, Center for Applied Medical Research CIMA, University of Navarra, IDISNA, Pamplona, Spain.<br /><searchLink fieldCode="AU" term="%22Martinez-Baztan+A%22">Martinez-Baztan A</searchLink>; Division of Hematology, Center for Applied Medical Research CIMA, University of Navarra, IDISNA, CIBERONC, Pamplona, Spain.<br /><searchLink fieldCode="AU" term="%22Paiva+B%22">Paiva B</searchLink>; Division of Hematology, Center for Applied Medical Research CIMA, University of Navarra, IDISNA, CIBERONC, Pamplona, Spain.<br /><searchLink fieldCode="AU" term="%22Moreno-Aliaga+MJ%22">Moreno-Aliaga MJ</searchLink>; Center for Nutrition Research and Department of Nutrition, Food Science and Physiology, University of Navarra, IDISNA, CIBEROBN, Pamplona, Spain.<br /><searchLink fieldCode="AU" term="%22Odero+MD%22">Odero MD</searchLink>; Division of Hematology, Center for Applied Medical Research CIMA, University of Navarra, IDISNA, CIBERONC, Pamplona, Spain.<br /><searchLink fieldCode="AU" term="%22Agirre+X%22">Agirre X</searchLink>; Division of Hematology, Center for Applied Medical Research CIMA, University of Navarra, IDISNA, CIBERONC, Pamplona, Spain.<br /><searchLink fieldCode="AU" term="%22Yanes+O%22">Yanes O</searchLink>; Universitat Rovira i Virgili, Department of Electronic Engineering, IISPV, CIBERDEM, Tarragona, Spain.<br /><searchLink fieldCode="AU" term="%22Prosper+F%22">Prosper F</searchLink>; Division of Hematology, Center for Applied Medical Research CIMA, University of Navarra, IDISNA, CIBERONC, Pamplona, Spain.; Department of Hematology, Clinica Universidad de Navarra, University of Navarra, IDISNA, CIBERONC, Pamplona, Spain.<br /><searchLink fieldCode="AU" term="%22Martinez-Climent+JA%22">Martinez-Climent JA</searchLink>; Division of Hematology, Center for Applied Medical Research CIMA, University of Navarra, IDISNA, CIBERONC, Pamplona, Spain. jamcliment@unav.es vfresquet@unav.es.
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  Data: <searchLink fieldCode="JN" term="%22101561693%22">Cancer discovery</searchLink> [Cancer Discov] 2021 May; Vol. 11 (5), pp. 1268-1285. <i>Date of Electronic Publication: </i>2020 Dec 18.
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